Dataset: Expression data from mouse kidney tissue
The role of the renin-angiotensin system in chronic kidney disease involves multiple peptides and receptors. Exerting antipodal...
The role of the renin-angiotensin system in chronic kidney disease involves multiple peptides and receptors. Exerting antipodal pathophysiological mechanisms, renin inhibition and AT1 antagonism ameliorate renal damage. This is a comparison between the renin inhibitor aliskiren with the At1 antagonist losartan in mice with chronic kidney disease due to renal ablation. Renal tissue from ablated mice was used after 6-week treatment with either 500 mg/l losartan or 50 mg/kg aliskiren per day (n = 5)
- Species:
- mouse
- Samples:
- 10
- Source:
- E-GEOD-34552
- PubMed:
- 22791343
- Updated:
- Dec.12, 2014
- Registered:
- Nov.12, 2014
Factors:
(via ArrayExpress)
| Sample | TREATMENT |
|---|---|
| GSM850915 | 500 mg/l losartan |
| GSM850915 | 500 mg/l losartan |
| GSM850915 | 500 mg/l losartan |
| GSM850915 | 500 mg/l losartan |
| GSM850915 | 500 mg/l losartan |
| GSM850920 | 50 mg/kg aliskiren |
| GSM850920 | 50 mg/kg aliskiren |
| GSM850920 | 50 mg/kg aliskiren |
| GSM850920 | 50 mg/kg aliskiren |
| GSM850920 | 50 mg/kg aliskiren |