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Home › Dataset Library › Gene expression changes in aortas of mice on high fat versus regular chow diet.

Dataset: Gene expression changes in aortas of mice on high fat versus regular chow diet.

To determine effects of hyperglycemia and insulin resistance on arterial wall biology, gene expression profiles were generated using...

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To determine effects of hyperglycemia and insulin resistance on arterial wall biology, gene expression profiles were generated using aortas from mice on high fat (35% fat) diet and their respective non diabetic regular chow fed controls. Keywords: Chip Experiment was done in triplicate with three independent pools from test mice on high fat diet and control mice on regular chow diet. For RNA isolation aortas were striped of adventitia and periaortic fat. RNA from three aortas was pooled for the synthesis of probe for affymetrix array analysis.

Species:
mouse

Samples:
6

Source:
E-GEOD-6735

PubMed:
18591389

Updated:
Dec.12, 2014

Registered:
Nov.23, 2014


Factors: (via ArrayExpress)
Sample STRAIN
GSM151940 C57BL/6J. Stock Number: 000664
GSM15194 C57BL/6J. Gender: male. Stock Number: 000664
GSM15194 C57BL/6J. Gender: male. Stock Number: 000664
GSM151943 C57BL/6J. Gender male. Stock Number: 000664
GSM151944 C57BL/6J. Gender male. Stock Number: 000664 26-28 weeks old
GSM151945 C57BL/6J. Gender male. Stock Number: 000664. 26-28 weeks old

Tags

  • adventitia
  • hyperglycemia
  • insulin

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