Dataset: Transcription profiling by array of mouse LSK hematopoietic stem cells from Cebpa K/K, K/L, and L/L knock-in mutants
Gene expression of LSK (lin-Sca-Kit+) hematopoietic stem cells from wild type mice was compared with LSK from Cebpa knock-in mutant mice...
Gene expression of LSK (lin-Sca-Kit+) hematopoietic stem cells from wild type mice was compared with LSK from Cebpa knock-in mutant mice (K/K, K/L, and L/L mutants). Fetal liver cells for each genotype were competitively transplanted into irradiant recipients. Donor-derived LSK cells were isolated by FACS sorting of recipient bone marrow. 3 biological replicates of each were generated and expression profiles were determined by hybridization to Affymetrix Moe430_2 arrays.
- Species:
- mouse
- Samples:
- 12
- Source:
- E-TABM-695
- PubMed:
- 19878871
- Updated:
- Dec.12, 2014
- Registered:
- Nov.21, 2014
Factors:
(via ArrayExpress)
| Sample | genotype |
|---|---|
| WT Mouse 1 | wild type |
| LL Mouse 1 | Cebpa L/L mutant |
| WT Mouse 1 | wild type |
| WT Mouse 1 | wild type |
| KK Mouse 1 | Cebpa K/K mutant |
| KK Mouse 1 | Cebpa K/K mutant |
| KK Mouse 1 | Cebpa K/K mutant |
| KL Mouse 1 | Cebpa K/L mutant |
| KL Mouse 1 | Cebpa K/L mutant |
| KL Mouse 1 | Cebpa K/L mutant |
| LL Mouse 1 | Cebpa L/L mutant |
| LL Mouse 1 | Cebpa L/L mutant |