Dataset: Transcription profiling by array of bone marrow and peripheral blood samples from childhood leukemia patients
We examined published microarray data from 104 acute lymphoblastic leukaemia patient specimens, that represent six different subgroups...
We examined published microarray data from 104 acute lymphoblastic leukaemia patient specimens, that represent six different subgroups defined by cytogenetic features and immunophenotypes. Using the decision-tree based supervised learning algorithm Random Forest (RF), we determined a small set of genes for optimal subgroup distinction and subsequently validated their predictive power in an independent cohort of 68 specimens that were assessed using Affymetrix HG-U133A arrays.
- Species:
- human
- Samples:
- 68
- Source:
- E-TABM-125
- PubMed:
- 17002788
- Updated:
- Dec.12, 2014
- Registered:
- Jun.20, 2014
Factors:
(via ArrayExpress)
| Sample | CHROMOSOMAL ABNORMALITY | INDIVIDUAL | CLINICAL HISTORY | ORGANISM PART | STRAIN |
|---|---|---|---|---|---|
| T-ALL-7 | patient 14 | prognostic subgroup: T-ALL | bone marrow | ||
| MLL-2 | MLL | patient 86 | prognostic subgroup: MLL | bone marrow | |
| T-ALL-9 | patient 21 | prognostic subgroup: T-ALL | bone marrow | ||
| Hyperdip50-10 | Hyperdip50 | patient 59 | prognostic subgroup: Hyperdip50 | bone marrow | |
| T-ALL-22 | patient 94 | prognostic subgroup: T-ALL | bone marrow | ||
| T-ALL-24 | prognostic subgroup: T-ALL | ALL-SIL | |||
| T-ALL-4 | patient 6 | prognostic subgroup: T-ALL | bone marrow | ||
| Hyperdip50-2 | Hyperdip50 | patient 18 | prognostic subgroup: Hyperdip50 | bone marrow | |
| T-ALL-14 | patient 33 | prognostic subgroup: T-ALL | bone marrow | ||
| T-ALL-2 | patient 3 | prognostic subgroup: T-ALL | bone marrow | ||
| Hyperdip50-15 | Hyperdip50 | patient 74 | prognostic subgroup: Hyperdip50 | bone marrow | |
| Hyperdip50-4 | Hyperdip50 | patient 34 | prognostic subgroup: Hyperdip50 | bone marrow | |
| T-ALL-33 | prognostic subgroup: T-ALL | PER-487 | |||
| Hyperdip50-13 | Hyperdip50 | patient 68 | prognostic subgroup: Hyperdip50 | bone marrow | |
| Hyperdip50-11 | Hyperdip50 | patient 61 | prognostic subgroup: Hyperdip50 | bone marrow | |
| BCR-ABL-1 | BCR-ABL | patient 16 | prognostic subgroup: BCR-ABL | bone marrow | |
| MLL-3 | MLL | patient 88 | prognostic subgroup: MLL | bone marrow | |
| T-ALL-21 | patient 33 | prognostic subgroup: T-ALL | peripheral blood | ||
| Hyperdip50-1 | Hyperdip50 | patient 5 | prognostic subgroup: Hyperdip50 | bone marrow | |
| T-ALL-8 | patient 17 | prognostic subgroup: T-ALL | bone marrow | ||
| TEL-AML1-1 | TEL-AML1 | prognostic subgroup: TEL-AML1 | PER-608 | ||
| T-ALL-20 | patient 27 | prognostic subgroup: T-ALL | peripheral blood | ||
| E2A-PBX1-1 | E2A-PBX1 | patient 47 | prognostic subgroup: E2A-PBX1 | bone marrow | |
| E2A-PBX1-2 | E2A-PBX1 | prognostic subgroup: E2A-PBX1 | PER-278 | ||
| T-ALL-36 | prognostic subgroup: T-ALL | PER-604 | |||
| T-ALL-37 | prognostic subgroup: T-ALL | PER-606 | |||
| T-ALL-31 | prognostic subgroup: T-ALL | PER-255 | |||
| T-ALL-13 | patient 27 | prognostic subgroup: T-ALL | bone marrow | ||
| T-ALL-1 | patient 2 | prognostic subgroup: T-ALL | bone marrow | ||
| T-ALL-11 | patient 24 | prognostic subgroup: T-ALL | bone marrow | ||
| T-ALL-32 | prognostic subgroup: T-ALL | PER-427 | |||
| BCR-ABL-3 | BCR-ABL | patient 25 | prognostic subgroup: BCR-ABL | bone marrow | |
| T-ALL-16 | patient 71 | prognostic subgroup: T-ALL | bone marrow | ||
| T-ALL-6 | patient 11 | prognostic subgroup: T-ALL | bone marrow | ||
| Hyperdip50-12 | Hyperdip50 | patient 65 | prognostic subgroup: Hyperdip50 | bone marrow | |
| T-ALL-11 | patient 24 | prognostic subgroup: T-ALL | bone marrow | ||
| T-ALL-26 | prognostic subgroup: T-ALL | DU528 | |||
| Hyperdip50-14 | Hyperdip50 | patient 73 | prognostic subgroup: Hyperdip50 | bone marrow | |
| T-ALL-19 | patient 26 | prognostic subgroup: T-ALL | bone marrow | ||
| Hyperdip50-17 | Hyperdip50 | patient 76 | prognostic subgroup: Hyperdip50 | bone marrow | |
| Hyperdip50-7 | Hyperdip50 | patient 48 | prognostic subgroup: Hyperdip50 | bone marrow | |
| T-ALL-30 | prognostic subgroup: T-ALL | PER-117 | |||
| T-ALL-35 | prognostic subgroup: T-ALL | PER-550 | |||
| MLL-4 | MLL | patient 90 | prognostic subgroup: MLL | bone marrow | |
| Hyperdip50-5 | Hyperdip50 | patient 43 | prognostic subgroup: Hyperdip50 | bone marrow | |
| MLL-5 | MLL | prognostic subgroup: MLL | PER-377 | ||
| T-ALL-29 | prognostic subgroup: T-ALL | MOLT4 | |||
| Hyperdip50-8 | Hyperdip50 | patient 50 | prognostic subgroup: Hyperdip50 | bone marrow | |
| Hyperdip50-16 | Hyperdip50 | patient 75 | prognostic subgroup: Hyperdip50 | bone marrow | |
| T-ALL-5 | patient 10 | prognostic subgroup: T-ALL | bone marrow | ||
| MLL-7 | MLL | prognostic subgroup: MLL | PER-490 | ||
| Hyperdip50-3 | Hyperdip50 | patient 20 | prognostic subgroup: Hyperdip50 | bone marrow | |
| T-ALL-10 | patient 23 | prognostic subgroup: T-ALL | bone marrow | ||
| T-ALL-15 | patient 41 | prognostic subgroup: T-ALL | bone marrow | ||
| T-ALL-25 | prognostic subgroup: T-ALL | CEM-CCRF | |||
| T-ALL-23 | prognostic subgroup: T-ALL | peripheral blood | |||
| T-ALL-18 | patient 24 | prognostic subgroup: T-ALL | peripheral blood | ||
| T-ALL-19 | patient 26 | prognostic subgroup: T-ALL | bone marrow | ||
| MLL-1 | MLL | patient 9 | prognostic subgroup: MLL | bone marrow | |
| BCR-ABL-3 | BCR-ABL | patient 25 | prognostic subgroup: BCR-ABL | bone marrow | |
| T-ALL-34 | prognostic subgroup: T-ALL | PER-537 | |||
| Hyperdip50-6 | Hyperdip50 | patient 45 | prognostic subgroup: Hyperdip50 | bone marrow | |
| T-ALL-28 | prognostic subgroup: T-ALL | Jurkat | |||
| T-ALL-3 | patient 4 | prognostic subgroup: T-ALL | bone marrow | ||
| MLL-6 | MLL | prognostic subgroup: MLL | PER-485 | ||
| T-ALL-27 | prognostic subgroup: T-ALL | HSB2 | |||
| E2A-PBX1-3 | E2A-PBX1 | prognostic subgroup: E2A-PBX1 | PER-371 | ||
| Hyperdip50-9 | Hyperdip50 | patient 56 | prognostic subgroup: Hyperdip50 | bone marrow |