Dataset: Transcription profiling of mouse CD1 wild types or induced diabetic littermates treated with human insulin and rat glucokinase
Many concurrent arrays were run for different projects. All test conditions were tested in all animal models. Animal models were (i)...
Many concurrent arrays were run for different projects. All test conditions were tested in all animal models. Animal models were (i) healthy CD1 mice (abbreviation CN), or (ii) STZ-induced diabetic CD1 littermates (STZ). Treatment conditions were (i) untreated animals (no prefix), (ii) treatment with 30ul saline and electrotransfer ("e" prefix), (iii) treatment with 75ug noncoding parental plasmid pGG2-CMV ("p" prefix), or (iv) treatment with 37.5ug each (75ug net) of pGG2-CMV-hIns and pGG2-CMV-rGck expressing human insulin and rat glucokinase respectively ("t" prefix). All samples were harvested 7 days after treatment.
- Species:
- mouse
- Samples:
- 25
- Source:
- E-MEXP-2191
- Updated:
- Dec.12, 2014
- Registered:
- Nov.24, 2014
Sample | COMPOUND | DiseaseState | DOSE |
---|---|---|---|
CN1 | untreated control | Healthy | 0 |
CN1 | untreated control | Healthy | 0 |
CN1 | untreated control | Healthy | 0 |
STZ1 | untreated control | STZ diabetic | 0 |
STZ1 | untreated control | STZ diabetic | 0 |
STZ1 | untreated control | STZ diabetic | 0 |
eCN1 | saline | Healthy | 0 |
eCN1 | saline | Healthy | 0 |
eCN1 | saline | Healthy | 0 |
eCN1 | saline | Healthy | 0 |
eSTZ1 | saline | STZ diabetic | 0 |
eSTZ1 | saline | STZ diabetic | 0 |
eSTZ1 | saline | STZ diabetic | 0 |
pCN1 | pGG2-CMV | Healthy | 75 |
pCN1 | pGG2-CMV | Healthy | 75 |
pCN1 | pGG2-CMV | Healthy | 75 |
pSTZ1 | pGG2-CMV | STZ diabetic | 75 |
pSTZ1 | pGG2-CMV | STZ diabetic | 75 |
pSTZ1 | pGG2-CMV | STZ diabetic | 75 |
tCN1 | pGG2-CMV-hINS and pGG2-CMV-rGck | Healthy | 75 |
tCN1 | pGG2-CMV-hINS and pGG2-CMV-rGck | Healthy | 75 |
tCN1 | pGG2-CMV-hINS and pGG2-CMV-rGck | Healthy | 75 |
tSTZ1 | pGG2-CMV-hINS and pGG2-CMV-rGck | STZ diabetic | 75 |
tSTZ1 | pGG2-CMV-hINS and pGG2-CMV-rGck | STZ diabetic | 75 |
tSTZ1 | pGG2-CMV-hINS and pGG2-CMV-rGck | STZ diabetic | 75 |