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Home › Dataset Library › Transcription profiling of mouse CD1 wild types or induced diabetic littermates treated with human insulin and rat glucokinase

Dataset: Transcription profiling of mouse CD1 wild types or induced diabetic littermates treated with human insulin and rat glucokinase

Many concurrent arrays were run for different projects. All test conditions were tested in all animal models. Animal models were (i)...

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Many concurrent arrays were run for different projects. All test conditions were tested in all animal models. Animal models were (i) healthy CD1 mice (abbreviation CN), or (ii) STZ-induced diabetic CD1 littermates (STZ). Treatment conditions were (i) untreated animals (no prefix), (ii) treatment with 30ul saline and electrotransfer ("e" prefix), (iii) treatment with 75ug noncoding parental plasmid pGG2-CMV ("p" prefix), or (iv) treatment with 37.5ug each (75ug net) of pGG2-CMV-hIns and pGG2-CMV-rGck expressing human insulin and rat glucokinase respectively ("t" prefix). All samples were harvested 7 days after treatment.

Species:
mouse

Samples:
25

Source:
E-MEXP-2191

Updated:
Dec.12, 2014

Registered:
Nov.24, 2014


Factors: (via ArrayExpress)
Sample DOSE DiseaseState COMPOUND
CN1 0 Healthy untreated control
CN1 0 Healthy untreated control
CN1 0 Healthy untreated control
STZ1 0 STZ diabetic untreated control
STZ1 0 STZ diabetic untreated control
STZ1 0 STZ diabetic untreated control
eCN1 0 Healthy saline
eCN1 0 Healthy saline
eCN1 0 Healthy saline
eCN1 0 Healthy saline
eSTZ1 0 STZ diabetic saline
eSTZ1 0 STZ diabetic saline
eSTZ1 0 STZ diabetic saline
pCN1 75 Healthy pGG2-CMV
pCN1 75 Healthy pGG2-CMV
pCN1 75 Healthy pGG2-CMV
pSTZ1 75 STZ diabetic pGG2-CMV
pSTZ1 75 STZ diabetic pGG2-CMV
pSTZ1 75 STZ diabetic pGG2-CMV
tCN1 75 Healthy pGG2-CMV-hINS and pGG2-CMV-rGck
tCN1 75 Healthy pGG2-CMV-hINS and pGG2-CMV-rGck
tCN1 75 Healthy pGG2-CMV-hINS and pGG2-CMV-rGck
tSTZ1 75 STZ diabetic pGG2-CMV-hINS and pGG2-CMV-rGck
tSTZ1 75 STZ diabetic pGG2-CMV-hINS and pGG2-CMV-rGck
tSTZ1 75 STZ diabetic pGG2-CMV-hINS and pGG2-CMV-rGck

Tags

  • insulin

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