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Home › Dataset Library › Transcription profiling of mouse CD1 wild types or induced diabetic littermates treated with human insulin and rat glucokinase

Dataset: Transcription profiling of mouse CD1 wild types or induced diabetic littermates treated with human insulin and rat glucokinase

Many concurrent arrays were run for different projects. All test conditions were tested in all animal models. Animal models were (i)...

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Many concurrent arrays were run for different projects. All test conditions were tested in all animal models. Animal models were (i) healthy CD1 mice (abbreviation CN), or (ii) STZ-induced diabetic CD1 littermates (STZ). Treatment conditions were (i) untreated animals (no prefix), (ii) treatment with 30ul saline and electrotransfer ("e" prefix), (iii) treatment with 75ug noncoding parental plasmid pGG2-CMV ("p" prefix), or (iv) treatment with 37.5ug each (75ug net) of pGG2-CMV-hIns and pGG2-CMV-rGck expressing human insulin and rat glucokinase respectively ("t" prefix). All samples were harvested 7 days after treatment.

Species:
mouse

Samples:
25

Source:
E-MEXP-2191

Updated:
Dec.12, 2014

Registered:
Nov.24, 2014


Factors: (via ArrayExpress)
Sample COMPOUND DiseaseState DOSE
CN1 untreated control Healthy 0
CN1 untreated control Healthy 0
CN1 untreated control Healthy 0
STZ1 untreated control STZ diabetic 0
STZ1 untreated control STZ diabetic 0
STZ1 untreated control STZ diabetic 0
eCN1 saline Healthy 0
eCN1 saline Healthy 0
eCN1 saline Healthy 0
eCN1 saline Healthy 0
eSTZ1 saline STZ diabetic 0
eSTZ1 saline STZ diabetic 0
eSTZ1 saline STZ diabetic 0
pCN1 pGG2-CMV Healthy 75
pCN1 pGG2-CMV Healthy 75
pCN1 pGG2-CMV Healthy 75
pSTZ1 pGG2-CMV STZ diabetic 75
pSTZ1 pGG2-CMV STZ diabetic 75
pSTZ1 pGG2-CMV STZ diabetic 75
tCN1 pGG2-CMV-hINS and pGG2-CMV-rGck Healthy 75
tCN1 pGG2-CMV-hINS and pGG2-CMV-rGck Healthy 75
tCN1 pGG2-CMV-hINS and pGG2-CMV-rGck Healthy 75
tSTZ1 pGG2-CMV-hINS and pGG2-CMV-rGck STZ diabetic 75
tSTZ1 pGG2-CMV-hINS and pGG2-CMV-rGck STZ diabetic 75
tSTZ1 pGG2-CMV-hINS and pGG2-CMV-rGck STZ diabetic 75

Tags

  • insulin

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