Dataset: Transcription profiling of human prostate cancer cells, normal epithelial prostatic cells and stroma cells from patients in placebo, selenium, vitamin E or selenium and vitamin E treatment groups

85 radical prostatectomy specimens (where 16 samples are in Placebo group (PL), 15 are in Selenium group (SE), 25 are in Vitamin E group...

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85 radical prostatectomy specimens (where 16 samples are in Placebo group (PL), 15 are in Selenium group (SE), 25 are in Vitamin E group (VE) and 27 are in Vitamin E & Selenium group (VS.Treatment groups: l-selenomethionine, 400 ug + placebo (vitamin E); vitamin E, 400 IU + placebo (l-selenomethionine); l-selenomethionine, 400 ug + vitamin E, 400 IU; placebos) were subjected to laser capture microdissection to isolate prostate cancer cells, normal epithelial prostatic cells, or stroma cells. RNA extraction and amplification were performed. Transcription profiling was conducted using the HG-U133A Affymetrix arrays.

Species:: human
Samples:: 85
Source:: E-MEXP-1327
Updated:: Dec.12, 2014
Registered:: Jun.19, 2014

Factors: (via ArrayExpress)

Sample	disease state	individual	cell type	compound
DI106JK selenium normal	normal	01NTPoBF2CCP	epithelial cell	selenium
DI118JK selenium stroma	normal	43NTPoBF2CCP	stroma	selenium
DI55JK placebo normal	normal	38PoBF2CCP	epithelial cell	placebo
DI63JK combo stroma	normal	17PoBF2CCP	stroma	selenium and vitamin E
DI34 combo tumor	prostate cancer tumor	03PoBF2CCP	tumor	selenium and vitamin E
DI97JK vitE normal	normal	48PoBF2CCP	epithelial cell	vitamin E
DI03 placebo tumor	prostate cancer tumor	02PoBF2CCP	tumor	placebo
DI73JK vitE tumor	prostate cancer tumor	04NTPoBF2CCP	tumor	vitamin E
DI14 placebo stroma	normal	09PoBF2CCP	stroma	placebo
DI04 placebo normal	normal	10PoBF2CCP	epithelial cell	placebo
DI02 placebo stroma	normal	02PoBF2CCP	stroma	placebo
DI105JK selenium tumor	prostate cancer tumor	13NTPoBF2CCP	tumor	selenium
DI121JK selenium tumor	prostate cancer tumor	44NTPoBF2CCP	tumor	selenium
DI96JK vitE tumor-stroma	prostate cancer tumor	47PoBF2CCP	stroma	vitamin E
DI54 combo tumor-stroma	prostate cancer tumor	40PoBF2CCP	stroma	selenium and vitamin E
DI64JK combo tumor	prostate cancer tumor	17PoBF2CCP	tumor	selenium and vitamin E
DI77JK vitE normal	normal	14NTPoBF2CCP	epithelial cell	vitamin E
DI141JKRe selenium stroma	normal	13NTPoBF2CCP	stroma	selenium
DI53 combo tumor	prostate cancer tumor	40PoBF2CCP	tumor	selenium and vitamin E
DI33 combo stroma	normal	03PoBF2CCP	stroma	selenium and vitamin E
DI102JK selenium normal	normal	13NTPoBF2CCP	epithelial cell	selenium
DI57JK combo normal	normal	08PoBF2CCP	epithelial cell	selenium and vitamin E
DI138JKRe vitE normal	normal	07NTPoBF2CCP	epithelial cell	vitamin E
DI78JK vitE stroma	normal	14NTPoBF2CCP	stroma	vitamin E
DI46 combo tumor	prostate cancer tumor	32PoBF2CCP	tumor	selenium and vitamin E
DI65JK combo normal	normal	18PoBF2CCP	epithelial cell	selenium and vitamin E
DI93JK vitE normal	normal	47PoBF2CCP	epithelial cell	vitamin E
DI91JK vitE normal	normal	45PoBF2CCP	epithelial cell	vitamin E
DI101JK selenium stroma	normal	05NTPoBF2CCP	stroma	selenium
DI116JK selenium stroma	normal	30NTPoBF2CCP	stroma	selenium
DI01 placebo normal	normal	02PoBF2CCP	epithelial cell	placebo
DI66JK combo stroma	normal	18PoBF2CCP	stroma	selenium and vitamin E
DI44 combo normal	normal	32PoBF2CCP	epithelial cell	selenium and vitamin E
DI81JK vitE normal	normal	20PoBF2CCP	epithelial cell	vitamin E
DI139JKRe vitE stroma	normal	07NTPoBF2CCP	stroma	vitamin E
DI56JK placebo stroma	normal	38PoBF2CCP	stroma	placebo
DI90JK vitE tumor	prostate cancer tumor	42PoBF2CCP	tumor	vitamin E
DI45 combo stroma	normal	32PoBF2CCP	stroma	selenium and vitamin E
DI100JK selenium normal	normal	05NTPoBF2CCP	epithelial cell	selenium
DI117JK selenium normal	normal	43NTPoBF2CCP	epithelial cell	selenium
DI115JK selenium normal	normal	30NTPoBF2CCP	epithelial cell	selenium
DI17 placebo normal	normal	25PoBF2CCP	epithelial cell	placebo
DI10 placebo normal	normal	46PoBF2CCP	epithelial cell	placebo
DI49 combo stroma	normal	35PoBF2CCP	stroma	selenium and vitamin E
DI60JK combo normal	normal	12PoBF2CCP	epithelial cell	selenium and vitamin E
DI67JK combo normal	normal	19PoBF2CCP	epithelial cell	selenium and vitamin E
DI82JK vitE tumor	prostate cancer tumor	20PoBF2CCP	tumor	vitamin E
DI89JK vitE stroma	normal	42PoBF2CCP	stroma	vitamin E
DI135JK placebo tumorstroma	prostate cancer tumor	10PoBF2CCP	stroma	placebo
DI113JK selenium normal	normal	24NTPoBF2CCP	epithelial cell	selenium
DI47 combo tumor stroma	prostate cancer tumor	32PoBF2CCP	stroma	selenium and vitamin E
DI59JK combo tumor	prostate cancer tumor	08PoBF2CCP	tumor	selenium and vitamin E
DI32 combo normal	normal	03PoBF2CCP	epithelial cell	selenium and vitamin E
DI83JK vitE normal	normal	27PoBF2CCP	epithelial cell	vitamin E
DI68JK combo stroma	normal	19PoBF2CCP	stroma	selenium and vitamin E
DI48 combo normal	normal	35PoBF2CCP	epithelial cell	selenium and vitamin E
DI09 placebo tumor	prostate cancer tumor	31PoBF2CCP	tumor	placebo
DI88JK vitE normal	normal	42PoBF2CCP	epithelial cell	vitamin E
DI137JK placebo stroma-tumor	prostate cancer tumor	46PoBF2CCP	stroma	placebo
DI18 placebo stroma	normal	25PoBF2CCP	stroma	placebo
DI06 placebo tumor	prostate cancer tumor	10PoBF2CCP	tumor	placebo
DI111JK selenium normal	normal	21NTPoBF2CCP	epithelial cell	selenium
DI69JK combo tumor	prostate cancer tumor	19PoBF2CCP	tumor	selenium and vitamin E
DI125JKRe vitE tumor	prostate cancer tumor	07NTPoBF2CCP	tumor	vitamin E
DI87JK vitE stroma	normal	37NTPoBF2CCP	stroma	vitamin E
DI62JK combo normal	normal	17PoBF2CCP	epithelial cell	selenium and vitamin E
DI70JK combo normal	normal	33PoBF2CCP	epithelial cell	selenium and vitamin E
DI84JK vitE stroma	normal	27PoBF2CCP	stroma	vitamin E
DI07 placebo normal	normal	31PoBF2CCP	epithelial cell	placebo
DI52 combo stroma	normal	40PoBF2CCP	stroma	selenium and vitamin E
DI99JK vitE tumor	prostate cancer tumor	48PoBF2CCP	tumor	vitamin E
DI142JKRe selenium stroma-tumor	prostate cancer tumor	13NTPoBF2CCP	stroma	selenium
DI107JK selenium stroma	normal	01NTPoBF2CCP	stroma	selenium
DI15 placebo normal	normal	22PoBF2CCP	epithelial cell	placebo
DI50 combo tumor	prostate cancer tumor	35PoBF2CCP	tumor	selenium and vitamin E
DI61JK combo stroma	normal	12PoBF2CCP	stroma	selenium and vitamin E
DI126JK vitE tumor-stroma	prostate cancer tumor	07NTPoBF2CCP	stroma	vitamin E
DI05 placebo stroma	normal	10PoBF2CCP	stroma	placebo
DI86JK vitE normal	normal	37NTPoBF2CCP	epithelial cell	vitamin E
DI98JK vitE stroma	normal	48PoBF2CCP	stroma	vitamin E
DI143JKRe vitE stroma	normal	20PoBF2CCP	stroma	vitamin E
DI72JK vitE normal	normal	04NTPoBF2CCP	epithelial cell	vitamin E
DI51 combo normal	normal	40PoBF2CCP	epithelial cell	selenium and vitamin E
DI85JK vitE tumor	prostate cancer tumor	27PoBF2CCP	tumor	vitamin E
DI13 placebo normal	normal	09PoBF2CCP	epithelial cell	placebo