Dataset: RNAi knock down of the DNA-repair enzyme and transcriptional co-activator APE1 in human HeLa cells

Transcriptional profiling was done following APE1/Ref1 silencing using conditional gene expression knockdown by RNA interference (RNAi) technology in HeLa cell lines. APE1 is a DNA-repair enzyme and transcriptional co-activator. Knockdown leads to cell-growth arrest, apoptosis and impairment in the intracellular redox state and cytoskeletal perturbation.

Species:

human

Samples:

6

Source:

E-MEXP-1315

PubMed:

19180539

Updated:

Dec.12, 2014

Registered:

Sep.22, 2014