Dataset: Transcription profiling of human monocyte-derived macrophages infected in vitro with wild type Leishmania chagasi parasites and then cultured with naive, autologous T-cells
We performed gene expression analysis using Affymetrix U133Plus2 microarray chips on cultures of infected human cells. To mimic an in...
We performed gene expression analysis using Affymetrix U133Plus2 microarray chips on cultures of infected human cells. To mimic an in vivo infection, we infected human monocyte-derived macrophages (MDMs) in vitro with wild-type L. chagasi parasites and then co-cultured those infected MDMs with naive, autologous T-cells.
- Species:
- human
- Samples:
- 16
- Source:
- E-MEXP-1290
- PubMed:
- 18575603
- Updated:
- Dec.12, 2014
- Registered:
- Sep.22, 2014
Factors:
(via ArrayExpress)
Sample | disease state | individual | cell type |
---|---|---|---|
MDM-Tcell1_Infected | Leishmania chagasi infected | Donor 1 | macrophage; T cell |
MDM-Tcell1_Uninfected | normal | Donor 1 | macrophage; T cell |
MDM-Tcell2_Infected | Leishmania chagasi infected | Donor 2 | macrophage; T cell |
MDM-Tcell2_Uninfected | normal | Donor 2 | macrophage; T cell |
MDM-Tcell3_Infected | Leishmania chagasi infected | Donor 3 | macrophage; T cell |
MDM-Tcell3_Uninfected | normal | Donor 3 | macrophage; T cell |
MDM-Tcell4_Infected | Leishmania chagasi infected | Donor 4 | macrophage; T cell |
MDM-Tcell4_Uninfected | normal | Donor 4 | macrophage; T cell |
MDM1_Infected | Leishmania chagasi infected | Donor 1 | macrophage |
MDM1_Uninfected | normal | Donor 1 | macrophage |
MDM2_Infected | Leishmania chagasi infected | Donor 2 | macrophage |
MDM2_Uninfected | normal | Donor 2 | macrophage |
MDM3_Infected | Leishmania chagasi infected | Donor 3 | macrophage |
MDM3_Uninfected | normal | Donor 3 | macrophage |
MDM4_Infected | Leishmania chagasi infected | Donor 4 | macrophage |
MDM4_Uninfected | normal | Donor 4 | macrophage |