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Home › Dataset Library › Transcription profiling of human monocyte-derived macrophages infected in vitro with wild type Leishmania chagasi parasites and then...

Dataset: Transcription profiling of human monocyte-derived macrophages infected in vitro with wild type Leishmania chagasi parasites and then cultured with naive, autologous T-cells

We performed gene expression analysis using Affymetrix U133Plus2 microarray chips on cultures of infected human cells. To mimic an in...

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We performed gene expression analysis using Affymetrix U133Plus2 microarray chips on cultures of infected human cells. To mimic an in vivo infection, we infected human monocyte-derived macrophages (MDMs) in vitro with wild-type L. chagasi parasites and then co-cultured those infected MDMs with naive, autologous T-cells.

Species:
human

Samples:
16

Source:
E-MEXP-1290

PubMed:
18575603

Updated:
Dec.12, 2014

Registered:
Sep.22, 2014


Factors: (via ArrayExpress)
Sample disease state individual cell type
MDM-Tcell1_Infected Leishmania chagasi infected Donor 1 macrophage; T cell
MDM-Tcell1_Uninfected normal Donor 1 macrophage; T cell
MDM-Tcell2_Infected Leishmania chagasi infected Donor 2 macrophage; T cell
MDM-Tcell2_Uninfected normal Donor 2 macrophage; T cell
MDM-Tcell3_Infected Leishmania chagasi infected Donor 3 macrophage; T cell
MDM-Tcell3_Uninfected normal Donor 3 macrophage; T cell
MDM-Tcell4_Infected Leishmania chagasi infected Donor 4 macrophage; T cell
MDM-Tcell4_Uninfected normal Donor 4 macrophage; T cell
MDM1_Infected Leishmania chagasi infected Donor 1 macrophage
MDM1_Uninfected normal Donor 1 macrophage
MDM2_Infected Leishmania chagasi infected Donor 2 macrophage
MDM2_Uninfected normal Donor 2 macrophage
MDM3_Infected Leishmania chagasi infected Donor 3 macrophage
MDM3_Uninfected normal Donor 3 macrophage
MDM4_Infected Leishmania chagasi infected Donor 4 macrophage
MDM4_Uninfected normal Donor 4 macrophage

Tags

  • monocyte

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