Dataset: Transcription profiling by array of human peripheral blood mononuclear cells in sepsis
To identify signature genes that help distinguish (1) sepsis from non-infectious causes of systemic inflammatory response syndrome, (2)...
To identify signature genes that help distinguish (1) sepsis from non-infectious causes of systemic inflammatory response syndrome, (2) between Gram-positive and Gram-negative sepsis. Experiment Overall Design: A total of 70 critically ill patients (46 sepsis and 24 control) were enrolled in a single-centre observational study. Gene-expression profiling was performed using Affymetrix microarray (U133plus2) with 54,675 transcript. Data was divided into a training set (n=35) and a validation set (n=35). A molecular signature was developed in the training set and was then validated in the validation set.
- Species:
- human
- Samples:
- 70
- Source:
- E-GEOD-9960
- PubMed:
- 19535937
- Updated:
- Dec.12, 2014
- Registered:
- Sep.22, 2014
Factors:
(via ArrayExpress)
| Sample | disease state | infection |
|---|---|---|
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251928 | Sepsis | Gram-positive and Gram-negative |
| GSE9960GSM251928 | Sepsis | Gram-positive and Gram-negative |
| GSE9960GSM251928 | Sepsis | Gram-positive and Gram-negative |
| GSE9960GSM251928 | Sepsis | Gram-positive and Gram-negative |
| GSE9960GSM251928 | Sepsis | Gram-positive and Gram-negative |
| GSE9960GSM251928 | Sepsis | Gram-positive and Gram-negative |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251928 | Sepsis | Gram-positive and Gram-negative |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251928 | Sepsis | Gram-positive and Gram-negative |
| GSE9960GSM251928 | Sepsis | Gram-positive and Gram-negative |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251928 | Sepsis | Gram-positive and Gram-negative |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251887 | Sepsis | Gram-Positive |
| GSE9960GSM251897 | Sepsis | Gram-Negative |
| GSE9960GSM251934 | systemic inflammatory response syndrome | none |