Dataset: Transcription profiling of mouse Primary Langerhans cells in animals treated with TCDD

The transcriptome of murine LC after 24 hours in vivo exposure to a moderate dose of 10 microgram 2,3,7,8-tetrachlorodibenzo-p-dioxin was studied. It was found that mice, although they express the arylhydrocarbon receptor abundantly in LC, are inert to its activation. Target genes are not inducible, in contrast to many other cell types. Experiment Overall Design: i.p. injection, isolation of cells after 24 hours, 95% sorting purity of LC.

Species:

mouse

Samples:

4

Source:

E-GEOD-9506

Updated:

Dec.12, 2014

Registered:

Nov.24, 2014