Dataset: Transcription profiling of mouse ire-deficient and wild-type littermate thymic medullary epithelial cells

We compared gene expression profiles of aire-deficient and wild-type littermate thymic medullary epithelial cells. This was done in order to determine whether Aire's effects differed among strains, and also among individuals of the same strain. Experiment Overall Design: Individual thymi were digested with collagenase, dispase and DNAse, and meduallary epithelial cells with the phenotype CD45-G8.8+Ly51intMHCclasssIIhi were isolated by FACS.

Species:

mouse

Samples:

20

Source:

E-GEOD-8564

Updated:

Dec.12, 2014

Registered:

Nov.18, 2014