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Home › Dataset Library › Expression data from AsPC1 cells treated with ICG-001

Dataset: Expression data from AsPC1 cells treated with ICG-001

The CREB binding protein inhibitor ICG-001 suppresses pancreatic cancer growth We used microarrays to detail global gene expression...

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The CREB binding protein inhibitor ICG-001 suppresses pancreatic cancer growth We used microarrays to detail global gene expression changes in the pancreatic cancer cell line AsPC1 following treatment with ICG-001 or siRNA-mediated knockdown of CTNNB1 (beta-catenin) AsPC1 cells were treated with 10uM ICG-001 or vehicle control (DMSO) for either 6 hours or 24 hours. AsPC-1 cells were also separately transfected with 20nM control siRNA or CTNNB1 siRNA for 48 hours. RNA was extracted at these time points for hybridization to Affymetrix microarrays

Species:
human

Samples:
16

Source:
E-GEOD-57728

Updated:
Dec.12, 2014

Registered:
Sep.21, 2014


Factors: (via ArrayExpress)
Sample TREATMENT
GSM1387688 10uM ICG-001, 6h
GSM1387688 10uM ICG-001, 6h
GSM1387688 10uM ICG-001, 6h
GSM138769 10uM ICG-001, 24h
GSM138769 10uM ICG-001, 24h
GSM138769 10uM ICG-001, 24h
GSM1387694 DMSO, 6h
GSM1387694 DMSO, 6h
GSM1387694 DMSO, 6h
GSM1387697 DMSO, 24h
GSM1387697 DMSO, 24h
GSM1387697 DMSO, 24h
GSM1387700 transfected with 20nM Ctrl siRNA, 48h
GSM1387700 transfected with 20nM Ctrl siRNA, 48h
GSM1387702 transfected with 20nM CTNNB1 siRNA, 48h
GSM1387702 transfected with 20nM CTNNB1 siRNA, 48h

Tags

  • cancer
  • cell
  • line
  • pancreatic cancer
  • protein

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