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Home › Dataset Library › Molecular effects of EtOH and Nicotine on normal human oral keratinocytes

Dataset: Molecular effects of EtOH and Nicotine on normal human oral keratinocytes

We have performed gene expression microarry analysis to profile molecular alterations in normal human oral keratinocytes that are induced...

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We have performed gene expression microarry analysis to profile molecular alterations in normal human oral keratinocytes that are induced by EtOH and/or nicotine. Our goal is to examine molecular signatures that are dysregulated by EtOH or nicotine and define the effects of co-use of alcohol and nicotine on normal oral epithelial cells and potentially on carcinogenesis. Primary normal human oral keratinocytes were cultured and treated with various dose of EtOH (0, 20 and 50 mM) and cotreated with various dose of nicotine (0, 0.5 and 1uM) for 24 hours. Total RNA was isolated and subjected to gene expression microarray analysis using Affymetrix Human Genome 2.0 plus.

Species:
human

Samples:
18

Source:
E-GEOD-57634

Updated:
Dec.12, 2014

Registered:
Jul.10, 2014


Factors: (via ArrayExpress)
Sample
GSM1385773 1
GSM1385772 1
GSM1385771 1
GSM1385770 1
GSM1385769 1
GSM1385768 1
GSM1385767 1
GSM1385766 1
GSM1385765 1
GSM1385764 1
GSM1385763 1
GSM1385762 1
GSM1385761 1
GSM1385760 1
GSM1385759 1
GSM1385758 1
GSM1385757 1
GSM1385756 1

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  • genome

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