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Home › Dataset Library › expression data of miR-21 knockdown in MCF-7

Dataset: expression data of miR-21 knockdown in MCF-7

miR-21 is overexpressed in breast cancer cells. Knock-down of miR-21 cause apoptosis and decreased cell proliferation. To identify miR-21...

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miR-21 is overexpressed in breast cancer cells. Knock-down of miR-21 cause apoptosis and decreased cell proliferation. To identify miR-21 regulated cancer-pathways in MCF-7 cells, we knocked-down miR-21 and performed microarray. RNA was harvested from MCF-7 cells 24 hours transfection of anti-control, anti-21, or untreated cells. RNA was processed and hybridized into Affymetrix whole human genome arrays in duplicates.

Species:
human

Samples:
6

Source:
E-GEOD-52674

Updated:
Dec.12, 2014

Registered:
Jul.11, 2014


Factors: (via ArrayExpress)
Sample TRANSFECTION
GSM1273929 untreated
GSM1273929 untreated
GSM1273927 anti-21 with lipofectamine 2000
GSM1273927 anti-21 with lipofectamine 2000
GSM1273925 anti-control with lipofectamine 2000
GSM1273925 anti-control with lipofectamine 2000

Tags

  • breast
  • breast cancer
  • cancer
  • cell
  • genome

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