Dataset: Transcription profiling of gulahuman CD8 T lyphocytes overexpressing hTERT to investigate regulation of profileration

Using CD8+ T lymphocyte clones over-expressing telomerase weinvestigated the molecular mechanisms that regulate T cell proliferation. Transduction and subcloning procedures were performed on CD8 + naive T-cell clones isolated from two different healthy individuals aged between 30 to 35 years (HD1 and HD2). T-cell cloneswere transduced to express hTERT/GFP or GFP alone. HD2 was profiled on U133Plus 2.0 and submitted as a separate GEO series. Experiment Overall Design: triplicates of 4 conditions, 1 chip (hTERT_YOUNG_HD1_REP2) excluded because of low quality hybridization.

Species:

human

Samples:

11

Source:

E-GEOD-5142

PubMed:

16951325

Updated:

Dec.12, 2014

Registered:

Jun.19, 2014