Dataset: Runx3 function in splenic NK cells (IL-2 or IL-15)

NK cells are innate immune cells that recognize and kill foreign, virally-infected and tumor cells without the need for prior immunization. NK expansion following viral infection is IL-2 or IL-15-dependent. To identify Runx3 responsive genes, NK cells were isolated from spleen of WT and Runx3-/- mice . Ten samples (5 WT and 5 Runx3-/-) of freshly isolated NK cells were separately obtained from individual mice. Cells were cultured for 7 days with IL-2 or IL-15.

Species:

mouse

Samples:

10

Source:

E-GEOD-50122

PubMed:

24236182

Updated:

Dec.12, 2014

Registered:

Nov.12, 2014