Dataset: Runx3 function in splenic NK cells (IL-2 or IL-15)
NK cells are innate immune cells that recognize and kill foreign, virally-infected and tumor cells without the need for prior...
NK cells are innate immune cells that recognize and kill foreign, virally-infected and tumor cells without the need for prior immunization. NK expansion following viral infection is IL-2 or IL-15-dependent. To identify Runx3 responsive genes, NK cells were isolated from spleen of WT and Runx3-/- mice . Ten samples (5 WT and 5 Runx3-/-) of freshly isolated NK cells were separately obtained from individual mice. Cells were cultured for 7 days with IL-2 or IL-15.
- Species:
- mouse
- Samples:
- 10
- Source:
- E-GEOD-50122
- PubMed:
- 24236182
- Updated:
- Dec.12, 2014
- Registered:
- Nov.12, 2014
Factors:
(via ArrayExpress)
Sample | TREATMENT | GENOTYPE |
---|---|---|
GSM1214465 | IL-2 | Runx3 +/+ |
GSM1214465 | IL-2 | Runx3 +/+ |
GSM1214465 | IL-2 | Runx3 +/+ |
GSM1214468 | IL-2 | Runx3 -/- |
GSM1214468 | IL-2 | Runx3 -/- |
GSM1214468 | IL-2 | Runx3 -/- |
GSM121447 | IL-15 | Runx3 +/+ |
GSM121447 | IL-15 | Runx3 +/+ |
GSM1214473 | IL-15 | Runx3 -/- |
GSM1214473 | IL-15 | Runx3 -/- |