Dataset: Re-specification of myeloid precursors from human pluripotent cells into engraftable multi-lineage progenitors

Human pluripotent stem cells were differentiated into hematopoietic progenitors, which were then re-specified using defined transcription factors to resemble hematopoietic stem cells (HSC) We used microarrays to establish the similarity between converted cells and purified human HSCs. The samples analyzed were: starting embryoid body progenitors, transcription factor-converted cells, and primary HSCs and progenitors from fetal liver and cord blood. All samples were flow sorted for CD34+ and CD38- to compare across a similar population of primitive cells.

Species:

human

Samples:

28

Source:

E-GEOD-49938

Updated:

Dec.12, 2014

Registered:

Jul.11, 2014