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Home › Dataset Library › KrasG12D partially compensates for the loss of beta-catenin in MLL-AF9 AML

Dataset: KrasG12D partially compensates for the loss of beta-catenin in MLL-AF9 AML

The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in MLL-AF9 AML. We evaluated the dependance on beta-...

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The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in MLL-AF9 AML. We evaluated the dependance on beta-catenin for KrasG12DMLL-AF9 leukemia. Lin-Kit+ bone marrow cells obtained from mice transplanted with primary MLL-AF9 leukemia cells and KRasG12DMLL-AF9 leukemia cells were assessed for gene expression in the presence or absence of beta-catenin

Species:
mouse

Samples:
12

Source:
E-GEOD-49248

PubMed:
24189294

Updated:
Dec.12, 2014

Registered:
Nov.12, 2014


Factors: (via ArrayExpress)
Sample
GSM1195957 1
GSM1195963 1
GSM1195964 1
GSM1195965 1
GSM1195966 1
GSM1195967 1
GSM1195968 1
GSM1195969 1
GSM1195970 1
GSM1195971 1
GSM1195972 1
GSM1195973 1

Tags

  • bone
  • bone marrow
  • leukemia

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