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Home › Dataset Library › Cyclin D1 determines estrogen depependent signaling in mouse mammary gland.

Dataset: Cyclin D1 determines estrogen depependent signaling in mouse mammary gland.

Ovariectomized virgin Ccnd1-/- and Ccnd1+/+ mice (5 weeks of age) were allowed to recuperate for 2 weeks. The mice were assigned to...

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Ovariectomized virgin Ccnd1-/- and Ccnd1+/+ mice (5 weeks of age) were allowed to recuperate for 2 weeks. The mice were assigned to either replacement pellets containing E2 (0.75 mg, 60-day release) or pellet containing placebo. Mice were sacrificed at day 7 after pellet implantation. RNA extracted from mammary glands (3 each group) was labeled and used to probe Affymetrix 430_2.0 arrays. Six separate control Ccnd1+/+ C57BL/6 were compared to six Ccnd1-/- C57BL/6 mice. 3 mice in each group treated with placebo and three mice treated with E2

Species:
mouse

Samples:
12

Source:
E-GEOD-48884

Updated:
Dec.12, 2014

Registered:
Nov.12, 2014


Factors: (via ArrayExpress)
Sample GENOTYPE TREATED WITH
GSM1186322 Ccnd1+/+ placebo control
GSM1186322 Ccnd1+/+ placebo control
GSM1186322 Ccnd1+/+ placebo control
GSM1186325 Ccnd1+/+ estradiol releasing pellets
GSM1186325 Ccnd1+/+ estradiol releasing pellets
GSM1186325 Ccnd1+/+ estradiol releasing pellets
GSM1186328 Ccnd1-/- placebo control
GSM1186328 Ccnd1-/- placebo control
GSM1186328 Ccnd1-/- placebo control
GSM118633 Ccnd1-/- estradiol releasing pellets
GSM118633 Ccnd1-/- estradiol releasing pellets
GSM118633 Ccnd1-/- estradiol releasing pellets

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