Dataset: Cyclin D1 determines estrogen depependent signaling in mouse mammary gland.
Ovariectomized virgin Ccnd1-/- and Ccnd1+/+ mice (5 weeks of age) were allowed to recuperate for 2 weeks. The mice were assigned to...
Ovariectomized virgin Ccnd1-/- and Ccnd1+/+ mice (5 weeks of age) were allowed to recuperate for 2 weeks. The mice were assigned to either replacement pellets containing E2 (0.75 mg, 60-day release) or pellet containing placebo. Mice were sacrificed at day 7 after pellet implantation. RNA extracted from mammary glands (3 each group) was labeled and used to probe Affymetrix 430_2.0 arrays. Six separate control Ccnd1+/+ C57BL/6 were compared to six Ccnd1-/- C57BL/6 mice. 3 mice in each group treated with placebo and three mice treated with E2
- Species:
- mouse
- Samples:
- 12
- Source:
- E-GEOD-48884
- Updated:
- Dec.12, 2014
- Registered:
- Nov.12, 2014
Factors:
(via ArrayExpress)
Sample | TREATED WITH | GENOTYPE |
---|---|---|
GSM1186322 | placebo control | Ccnd1+/+ |
GSM1186322 | placebo control | Ccnd1+/+ |
GSM1186322 | placebo control | Ccnd1+/+ |
GSM1186325 | estradiol releasing pellets | Ccnd1+/+ |
GSM1186325 | estradiol releasing pellets | Ccnd1+/+ |
GSM1186325 | estradiol releasing pellets | Ccnd1+/+ |
GSM1186328 | placebo control | Ccnd1-/- |
GSM1186328 | placebo control | Ccnd1-/- |
GSM1186328 | placebo control | Ccnd1-/- |
GSM118633 | estradiol releasing pellets | Ccnd1-/- |
GSM118633 | estradiol releasing pellets | Ccnd1-/- |
GSM118633 | estradiol releasing pellets | Ccnd1-/- |