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Home › Dataset Library › Runx1 deficiency effect on MLL-ENL cells

Dataset: Runx1 deficiency effect on MLL-ENL cells

To identify the target genes of Runx1 in MLL fusion leukemia, we performed microarray analysis using control and Runx1-deficient MLL-ENL...

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To identify the target genes of Runx1 in MLL fusion leukemia, we performed microarray analysis using control and Runx1-deficient MLL-ENL leukemia cells. Runx1 intact and excised bone marrow cells were transduced with MLL-ENL and transplanted into congenic mice. Leukemic cells were harvested from moribund mice, and gene expression was compared using 3 independent leukemia cells for each genotype.

Species:
mouse

Samples:
6

Source:
E-GEOD-47402

Updated:
Dec.12, 2014

Registered:
Nov.12, 2014


Factors: (via ArrayExpress)
Sample GENOTYPE
GSM1148917 Runx1-KO
GSM1148917 Runx1-KO
GSM1148917 Runx1-KO
GSM1148920 Runx1-intact
GSM1148920 Runx1-intact
GSM1148920 Runx1-intact

Tags

  • bone
  • bone marrow
  • leukemia

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