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Home › Dataset Library › Molecular profiles of cognitive aging

Dataset: Molecular profiles of cognitive aging

Gene expression was measured from the dentate gyrus and entorhinal cortex harvested from human postmortem samples. We harvested the...

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Gene expression was measured from the dentate gyrus and entorhinal cortex harvested from human postmortem samples. We harvested the dentate gyrus DG from healthy human brains ranging from 33 to 88 years of age. Additionally, from each brain we harvested the entorhinal cortex (EC) as a within-brain control. Using Affymetrix microarray chips we generated gene-expression profiles of each individual tissue samples. DG expression levels were first normalized against the EC, and the normalized DG transcripts were then correlated against age.

Species:
human

Samples:
16

Source:
E-GEOD-46193

Updated:
Dec.12, 2014

Registered:
Jun.18, 2014


Factors: (via ArrayExpress)
Sample AGE INDIVIDUAL ORGANISM PART
GSM112598 57 subject #8 entorhinal cortex
GSM1125980 57 subject #8 dentate gyrus
GSM1125979 64 subject #7 entorhinal cortex
GSM1125978 64 subject #7 dentate gyrus
GSM1125977 33 subject #6 entorhinal cortex
GSM1125976 33 subject #6 dentate gyrus
GSM1125975 55 subject #5 entorhinal cortex
GSM1125974 55 subject #5 dentate gyrus
GSM1125973 44 subject #4 entorhinal cortex
GSM1125972 44 subject #4 dentate gyrus
GSM112597 33 subject #3 entorhinal cortex
GSM1125970 33 subject #3 dentate gyrus
GSM1125969 84 subject #2 dentate gyrus
GSM1125968 84 subject #2 entorhinal cortex
GSM1125967 81 subject #1 dentate gyrus
GSM1125966 81 subject #1 entorhinal cortex

Tags

  • brain
  • cortex

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