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Home › Dataset Library › Expression data from wild-type and HMGN1 knockout mice injected with N-nitrosodiethylamine

Dataset: Expression data from wild-type and HMGN1 knockout mice injected with N-nitrosodiethylamine

HMGN1 contributes to the shortened latency of liver tumorigenesis by changing a chromatin structure and expression of relevant genes To...

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HMGN1 contributes to the shortened latency of liver tumorigenesis by changing a chromatin structure and expression of relevant genes To assess the molecular mechanisms underlying accelerated tumor development in Hmgn1-/- mice, we performed the gene expression profiling of liver cells at early stages Expression profiles has been compared between Hmgn1+/+ and Hmgn1-/- mice livers at 4 weeks after birth and at 12 weeks after DEN or saline (control) injection at 4 weeks

Species:
mouse

Samples:
18

Source:
E-GEOD-44356

Updated:
Dec.12, 2014

Registered:
Nov.12, 2014


Factors: (via ArrayExpress)
Sample GENOTYPE TREATMENT
GSM1083886 Hmgn1+/+ none
GSM1083886 Hmgn1+/+ none
GSM1083886 Hmgn1+/+ none
GSM1083889 Hmgn1-/- none
GSM1083889 Hmgn1-/- none
GSM1083889 Hmgn1-/- none
GSM1083892 Hmgn1+/+ injection of 10 �g/g body weight of N-nitrosodiethylamine
GSM1083892 Hmgn1+/+ injection of 10 �g/g body weight of N-nitrosodiethylamine
GSM1083892 Hmgn1+/+ injection of 10 �g/g body weight of N-nitrosodiethylamine
GSM1083895 Hmgn1-/- injection of 10 �g/g body weight of N-nitrosodiethylamine
GSM1083895 Hmgn1-/- injection of 10 �g/g body weight of N-nitrosodiethylamine
GSM1083895 Hmgn1-/- injection of 10 �g/g body weight of N-nitrosodiethylamine
GSM1083898 Hmgn1+/+ injection of 10 �g/g body weight of saline
GSM1083898 Hmgn1+/+ injection of 10 �g/g body weight of saline
GSM1083898 Hmgn1+/+ injection of 10 �g/g body weight of saline
GSM108390 Hmgn1-/- injection of 10 �g/g body weight of saline
GSM108390 Hmgn1-/- injection of 10 �g/g body weight of saline
GSM108390 Hmgn1-/- injection of 10 �g/g body weight of saline

Tags

  • chromatin
  • liver

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