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Home › Dataset Library › C/EBPa gene signature

Dataset: C/EBPa gene signature

We defined the C/EBPa signature characterized by a set of genes which are upregulated upon C/EBPa activation. In order to identify the...

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We defined the C/EBPa signature characterized by a set of genes which are upregulated upon C/EBPa activation. In order to identify the C/EBPa signature, we performed microarray gene expression analysis of K562 cells stably expressing p42-C/EBPa-ER after activating the C/EBPa construct to translocate to the nucleus for 6 hours with beta-estradiol. The gene expression profile was performed in K562 p42-C/EBPa-ER expressing cells treated with beta-estradiol (n=4) or EtOH vehicle control (n-4) for 6 hours. Induction of nuclear localization of C/EBPa-ER fusion protein was achieved by addition of 1 uM beta-estradiol as indicated into the culture medium.

Species:
human

Samples:
8

Source:
E-GEOD-43998

Updated:
Dec.12, 2014

Registered:
Jul.12, 2014


Factors: (via ArrayExpress)
Sample TREATMENT
GSM1076324 ethanol vehicle control
GSM1076324 ethanol vehicle control
GSM1076324 ethanol vehicle control
GSM1076324 ethanol vehicle control
GSM1076320 beta-estradiol
GSM1076320 beta-estradiol
GSM1076320 beta-estradiol
GSM1076320 beta-estradiol

Tags

  • protein

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