ArrayExpress Uploader0humanethanol vehicle controlethanol vehicle controlethanol vehicle controlethanol vehicle controlbeta-estradiolbeta-estradiolbeta-estradiolbeta-estradiol2487arrayexpress_sid4We defined the C/EBPa signature characterized by a set of genes which are upregulated upon C/EBPa activation. In order to identify the...E-GEOD-43998/profile/8773/arrayexpressuploader18proteinDec.12, 2014Falsecebpa-gene-signatureE-GEOD-43998_A-AFFY-44C/EBPa gene signatureJul.12, 2014We defined the C/EBPa signature characterized by a set of genes which are upregulated upon C/EBPa activation. In order to identify the C/EBPa signature, we performed microarray gene expression analysis of K562 cells stably expressing p42-C/EBPa-ER after activating the C/EBPa construct to translocate to the nucleus for 6 hours with beta-estradiol. The gene expression profile was performed in K562 p42-C/EBPa-ER expressing cells treated with beta-estradiol (n=4) or EtOH vehicle control (n-4) for 6 hours. Induction of nuclear localization of C/EBPa-ER fusion protein was achieved by addition of 1 uM beta-estradiol as indicated into the culture medium.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-43998http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-43998/samples/