Dataset: Transcription profiling of human atrial tissue from patients undergoing coronary artery bypass graft surgery to determine the effect of anesthesia on gene expression

Anesthetic gases elicit organ protection in patients undergoing coronary artery bypass graft (CABG) surgery. This study aimed at identifying myocardial transcriptional phenotypes and anesthetic-induced changes in gene expression to predict cardiovascular biomarkers and cardiac function after off-pump CABG. Experiment Overall Design: Patients scheduled for off-pump CABG were randomized into a group with the anesthetic gas sevoflurane (n=10) or the intravenous anesthetic propofol (n=10). Atrial samples were collected at the beginning and end of bypass surgery to determine gene expression profiles.

Species:

human

Samples:

40

Source:

E-GEOD-4386

PubMed:

17325502

Updated:

Dec.12, 2014

Registered:

Sep.19, 2014