Dataset: Expression data from meningiomas and normal meninges

Correlate the gene expression profiles with the most relevant patterns of chromosome abnormalities (cytogenetic subgroups of meningiomas)...

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Correlate the gene expression profiles with the most relevant patterns of chromosome abnormalities (cytogenetic subgroups of meningiomas) and the gene expression profiles could help to explain the differences in clinical behaviour of meningiomas. The impact of tumor cytogenetics on the gene expression analyzed in meningiomas. Here, we analyzed the gene expression profiles (GEP) of 47 tumors and correlated them with the most clinical relevant cytogenetic subgroups of meningiomas, including diploid tumors, isolated -22/22q-, del(1p36) alone and complex karyotypes associated with del(1p36) and/or -14q. In addition, 4 samples containing purified RNA extracted from normal meningeal cells (BioChain Institute, Hayward, CA and US Biological, Swampscott, MA, USA) were also processed.

Species:: human
Samples:: 51
Source:: E-GEOD-43290
Updated:: Dec.12, 2014
Registered:: Jun.18, 2014

Factors: (via ArrayExpress)

Sample	CYTOGENETIC GROUP	AGE	CODE SAMPLEBRAINPATHOLMS	SUBMITTED	SEX	PATIENTCODEONCOLOGISTMS	HISTOLOGY	WHO GRADE
GSM1060115	Normal meninge lot nï¿½ A503203	24	M4	not included	male	Not included	normal meninge	Not applicable
GSM1060114	Normal meninge lot nï¿½ L5102059	29	M3	not included	male	Not included	normal meninge	Not applicable
GSM1060113	Normal meninge lot nï¿½ A602330	29	M2	not included	male	Not included	normal meninge	Not applicable
GSM1060112	Normal meninge lot nï¿½ A6903225	82	M1	not included	female	Not included	normal meninge	Not applicable
GSM1060	del 1p/Loss 1p	80	DEL1/4	not included	female	37	Meningothelial	I
GSM1060110	del 1p/Loss 1p	68	DEL1/3	not included	female	36	Psammomatous	I
GSM1060109	del 1p/Loss 1p	73	DEL1/2	not included	female	35	Meningothelial	I
GSM1060108	del 1p/Loss 1p	66	DEL1/1	not included	male	8	Fibroblastic	I
GSM1060107	Complex karyotype	62	CK/13	16B	female	Not included	Atypical	II
GSM1060106	Complex karyotype	41	CK/12	9	male	12	Atypical	II
GSM1060105	Complex karyotype	75	CK/11	5B	male	11	Transitional	I
GSM1060104	Complex karyotype	73	CK/10	5A	male	10	Meningothelial	I
GSM1060103	Complex karyotype	30	CK/9	4A	female	45	Anaplastic	III
GSM1060102	Complex karyotype	70	CK/8	19	female	44	Transitional	I
GSM106010	Complex karyotype	52	CK/7	18	female	43	Atypical	II
GSM1060100	Complex karyotype	60	CK/6	16A	female	42	Transitional	I
GSM1060099	Complex karyotype	23	CK/5	7	male	9	Atypical	II
GSM1060098	Complex karyotype	76	CK/4	13	female	41	Meningothelial	I
GSM1060097	Complex karyotype	35	CK/3	11	female	40	Atypical	II
GSM1060096	Complex karyotype	30	CK/2	not included	female	39	Atypical-Papillary	III
GSM1060095	Complex karyotype	64	CK/1	2	female	38	Atypical	II
GSM1060094	del22q/Monosomy 22	53	M22/12	40	female	34	Fibroblastic	I
GSM1060093	del22q/Monosomy 22	65	M22/11	39	female	33	Psammomatous	I
GSM1060092	del22q/Monosomy 22	34	M22/10	33	female	30	Fibroblastic	I
GSM106009	del22q/Monosomy 22	74	M22/9	29	female	29	Atypical	II
GSM1060090	del22q/Monosomy 22	54	M22/8	15	male	7	Psammomatous	I
GSM1060089	del22q/Monosomy 22	54	M22/7	23	female	28	Psammomatous	I
GSM1060088	del22q/Monosomy 22	76	M22/6	22	male	6	Transitional	I
GSM1060087	del22q/Monosomy 22	81	M22/5	21	female	27	Psammomatous	I
GSM1060086	del22q/Monosomy 22	77	M22/4	6	female	32	Transitional	I
GSM1060085	del22q/Monosomy 22	59	M22/3	12	female	26	Psammomatous	I
GSM1060084	del22q/Monosomy 22	72	M22/2	3	female	25	Psammomatous	I
GSM1060083	del22q/Monosomy 22	76	M22/1	1	female	31	Fibroblastic	I
GSM1060082	Diploid (autosomes) with -Y	65	D/19	not included	male	Not included	Meningothelial	I
GSM106008	Diploid	54	D/18	37	female	24	Atypical	II
GSM1060080	Diploid	65	D/17	36	male	5	Atypical	II
GSM1060079	Diploid	47	D/16	35	female	23	Meningothelial	I
GSM1060078	Diploid	54	D/15	32	male	4	Transitional	I
GSM1060077	Diploid	77	D/14	31	male	3	Transitional	I
GSM1060076	Diploid	66	D/13	not included	male	2	Atypical	II
GSM1060075	Diploid	69	D/12	30	female	22	Meningothelial	I
GSM1060074	Diploid	68	D/11	28	female	21	Transitional	I
GSM1060073	Diploid	36	D/10	27	female	20	Transitional	I
GSM1060072	Diploid	84	D/9	26	female	19	Secretory	I
GSM106007	Diploid	63	D/8	25	female	18	Psammomatous	I
GSM1060070	Diploid	68	D/7	24	female	17	Transitional	I
GSM1060069	Diploid	56	D/5	20	male	1	Transitional	I
GSM1060068	Diploid	73	D/4	17	female	16	Transitional	I
GSM1060067	Diploid	76	D/3	14	female	15	Transitional	I
GSM1060066	Diploid	62	D/2	10	female	14	Atypical	II
GSM1060065	Diploid	62	D/1	8	female	13	Atypical	II