Dataset: Expression data from meningiomas and normal meninges

Correlate the gene expression profiles with the most relevant patterns of chromosome abnormalities (cytogenetic subgroups of meningiomas)...

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Correlate the gene expression profiles with the most relevant patterns of chromosome abnormalities (cytogenetic subgroups of meningiomas) and the gene expression profiles could help to explain the differences in clinical behaviour of meningiomas. The impact of tumor cytogenetics on the gene expression analyzed in meningiomas. Here, we analyzed the gene expression profiles (GEP) of 47 tumors and correlated them with the most clinical relevant cytogenetic subgroups of meningiomas, including diploid tumors, isolated -22/22q-, del(1p36) alone and complex karyotypes associated with del(1p36) and/or -14q. In addition, 4 samples containing purified RNA extracted from normal meningeal cells (BioChain Institute, Hayward, CA and US Biological, Swampscott, MA, USA) were also processed.

Species:: human
Samples:: 51
Source:: E-GEOD-43290
Updated:: Dec.12, 2014
Registered:: Jun.18, 2014

Factors: (via ArrayExpress)

Sample	PATIENTCODEONCOLOGISTMS	AGE	CODE SAMPLEBRAINPATHOLMS	SUBMITTED	SEX	CYTOGENETIC GROUP	HISTOLOGY	WHO GRADE
GSM1060115	Not included	24	M4	not included	male	Normal meninge lot nï¿½ A503203	normal meninge	Not applicable
GSM1060114	Not included	29	M3	not included	male	Normal meninge lot nï¿½ L5102059	normal meninge	Not applicable
GSM1060113	Not included	29	M2	not included	male	Normal meninge lot nï¿½ A602330	normal meninge	Not applicable
GSM1060112	Not included	82	M1	not included	female	Normal meninge lot nï¿½ A6903225	normal meninge	Not applicable
GSM1060	37	80	DEL1/4	not included	female	del 1p/Loss 1p	Meningothelial	I
GSM1060110	36	68	DEL1/3	not included	female	del 1p/Loss 1p	Psammomatous	I
GSM1060109	35	73	DEL1/2	not included	female	del 1p/Loss 1p	Meningothelial	I
GSM1060108	8	66	DEL1/1	not included	male	del 1p/Loss 1p	Fibroblastic	I
GSM1060107	Not included	62	CK/13	16B	female	Complex karyotype	Atypical	II
GSM1060106	12	41	CK/12	9	male	Complex karyotype	Atypical	II
GSM1060105	11	75	CK/11	5B	male	Complex karyotype	Transitional	I
GSM1060104	10	73	CK/10	5A	male	Complex karyotype	Meningothelial	I
GSM1060103	45	30	CK/9	4A	female	Complex karyotype	Anaplastic	III
GSM1060102	44	70	CK/8	19	female	Complex karyotype	Transitional	I
GSM106010	43	52	CK/7	18	female	Complex karyotype	Atypical	II
GSM1060100	42	60	CK/6	16A	female	Complex karyotype	Transitional	I
GSM1060099	9	23	CK/5	7	male	Complex karyotype	Atypical	II
GSM1060098	41	76	CK/4	13	female	Complex karyotype	Meningothelial	I
GSM1060097	40	35	CK/3	11	female	Complex karyotype	Atypical	II
GSM1060096	39	30	CK/2	not included	female	Complex karyotype	Atypical-Papillary	III
GSM1060095	38	64	CK/1	2	female	Complex karyotype	Atypical	II
GSM1060094	34	53	M22/12	40	female	del22q/Monosomy 22	Fibroblastic	I
GSM1060093	33	65	M22/11	39	female	del22q/Monosomy 22	Psammomatous	I
GSM1060092	30	34	M22/10	33	female	del22q/Monosomy 22	Fibroblastic	I
GSM106009	29	74	M22/9	29	female	del22q/Monosomy 22	Atypical	II
GSM1060090	7	54	M22/8	15	male	del22q/Monosomy 22	Psammomatous	I
GSM1060089	28	54	M22/7	23	female	del22q/Monosomy 22	Psammomatous	I
GSM1060088	6	76	M22/6	22	male	del22q/Monosomy 22	Transitional	I
GSM1060087	27	81	M22/5	21	female	del22q/Monosomy 22	Psammomatous	I
GSM1060086	32	77	M22/4	6	female	del22q/Monosomy 22	Transitional	I
GSM1060085	26	59	M22/3	12	female	del22q/Monosomy 22	Psammomatous	I
GSM1060084	25	72	M22/2	3	female	del22q/Monosomy 22	Psammomatous	I
GSM1060083	31	76	M22/1	1	female	del22q/Monosomy 22	Fibroblastic	I
GSM1060082	Not included	65	D/19	not included	male	Diploid (autosomes) with -Y	Meningothelial	I
GSM106008	24	54	D/18	37	female	Diploid	Atypical	II
GSM1060080	5	65	D/17	36	male	Diploid	Atypical	II
GSM1060079	23	47	D/16	35	female	Diploid	Meningothelial	I
GSM1060078	4	54	D/15	32	male	Diploid	Transitional	I
GSM1060077	3	77	D/14	31	male	Diploid	Transitional	I
GSM1060076	2	66	D/13	not included	male	Diploid	Atypical	II
GSM1060075	22	69	D/12	30	female	Diploid	Meningothelial	I
GSM1060074	21	68	D/11	28	female	Diploid	Transitional	I
GSM1060073	20	36	D/10	27	female	Diploid	Transitional	I
GSM1060072	19	84	D/9	26	female	Diploid	Secretory	I
GSM106007	18	63	D/8	25	female	Diploid	Psammomatous	I
GSM1060070	17	68	D/7	24	female	Diploid	Transitional	I
GSM1060069	1	56	D/5	20	male	Diploid	Transitional	I
GSM1060068	16	73	D/4	17	female	Diploid	Transitional	I
GSM1060067	15	76	D/3	14	female	Diploid	Transitional	I
GSM1060066	14	62	D/2	10	female	Diploid	Atypical	II
GSM1060065	13	62	D/1	8	female	Diploid	Atypical	II