Dataset: Gene expression analysis of human CD4+ T cells differentiated into Th17 cells in the presence of high-salt

Th17 cells are believed to be a critical cell population for driving autoimmune diseases. However, environmental factors that are directly related to the development of Th17 cells are largely unknown. High-salt (NaCl) concentrations enhance Th17 differentiation of human naive CD4+ T cells in vitro. The aim of the study was to analyse the changes in gene expression induced by high-salt conditions during Th17 differentiation. Naive human CD4+ T cells were in vitro differentiated into Th17 cells in the presence or absence of high-salt. We arrayed 2 different donors for each condition (control & high-salt).

Species:

human

Samples:

4

Source:

E-GEOD-42569

Updated:

Dec.12, 2014

Registered:

Jul.12, 2014