Dataset: Expression data from post-transplant lymphoproliferative disorder (PTLD) patient samples
In this study we focussed on malignant post-transplant lymphomas. Post-transplant lymphoma is strongly associated with Epstein-Barr Virus...
In this study we focussed on malignant post-transplant lymphomas. Post-transplant lymphoma is strongly associated with Epstein-Barr Virus (EBV) infection in contrast to lymphoma arising in an immunocompetent population. Nevertheless, about 1 in 3 PTLD cases are negative for EBV. We used a microarray to define the gene expression profile of different PTLDs to elucidate the pathogenesis of EBV(+) and EBV(-) PTLD and to define whether EBV(-) PTLD is biologically different from EBV(-) lymphoma arising in an immunocompetent host. PTLD patient samples were randomly selected for RNA extraction and hybridization on an Affymetrix platform. The post-transplant tumors consisted of homogenous sheets of neoplastic cells ensuring reliability of the gene expression data.
- Species:
- human
- Samples:
- 65
- Source:
- E-GEOD-38885
- Updated:
- Dec.12, 2014
- Registered:
- Sep.19, 2014
Sample | CHIP NUMBER | ORGANISM PART | EBV STATUS | LYMPHOMA SUBTYPE | IMMUNE STATUS |
---|---|---|---|---|---|
GSM951416 | 10706 | Gut-associated lymphoid tissue | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951417 | 6597 | Gut-associated lymphoid tissue | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951418 | 10676 | testis | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951419 | 6554 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951420 | 6566 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM95142 | 6569 | Gut-associated lymphoid tissue | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951422 | 6592 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951423 | 6606 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951424 | 6556 | Gut-associated lymphoid tissue | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951425 | 10730 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951426 | 10712 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951427 | 10715 | Waldeyer | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951428 | 6580 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951429 | 10681 | Gut-associated lymphoid tissue | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951430 | 6568 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM95143 | 10675 | Waldeyer | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951432 | 10690 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951433 | 10709 | Waldeyer | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951434 | 6593 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951435 | 10724 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951436 | 6575 | Urinary tract | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951437 | 10703 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951438 | 6599 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951439 | 10697 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951440 | 6562 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM95144 | 10727 | Gut-associated lymphoid tissue | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951442 | 10685 | BALT | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951443 | 10688 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951444 | 6571 | Urinary tract | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951445 | 6564 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951446 | 10682 | lymph node | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951447 | 6694 | Gut-associated lymphoid tissue | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951448 | 6579 | Gut-associated lymphoid tissue | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
GSM951449 | 6595 | lymph node | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Post-transplant lymphoma |
GSM951450 | 6582 | Waldeyer | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Post-transplant lymphoma |
GSM95145 | 10696 | lymph node | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Post-transplant lymphoma |
GSM951452 | 6602 | lymph node | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Post-transplant lymphoma |
GSM951453 | 6585 | lymph node | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Post-transplant lymphoma |
GSM951454 | 6590 | lymph node | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Post-transplant lymphoma |
GSM951455 | 10733 | Gut-associated lymphoid tissue | EBV(+) | Burkitt Lymphoma | Post-transplant lymphoma |
GSM951456 | 6598 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951457 | 6561 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951458 | 10710 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951459 | 6607 | mediastinum | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951460 | 10692 | Gut-associated lymphoid tissue | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM95146 | 6603 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951462 | 6600 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951463 | 6573 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951464 | 6576 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951465 | 6587 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951466 | 6596 | Extracranial fronto-parietal | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951467 | 10683 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951468 | 6563 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951469 | 10728 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951470 | 6581 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM95147 | 6570 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951472 | 10719 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951473 | 10714 | lymph node | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
GSM951474 | 6589 | lymph node | EBV(-) | DLBCL (Burkitt-like lymphoma (BLL)) | Immunocompetent lymphoma |
GSM951475 | 10725 | lymph node | EBV(-) | DLBCL (Burkitt-like lymphoma (BLL)) | Immunocompetent lymphoma |
GSM951476 | 10686 | Gut-associated lymphoid tissue | EBV(-) | DLBCL (Burkitt-like lymphoma (BLL)) | Immunocompetent lymphoma |
GSM951477 | 10713 | lymph node | EBV(-) | Burkitt Lymphoma | Immunocompetent lymphoma |
GSM951478 | 10677 | lymph node | EBV(-) | Burkitt Lymphoma | Immunocompetent lymphoma |
GSM951479 | 10695 | lymph node | EBV(-) | Burkitt Lymphoma | Immunocompetent lymphoma |
GSM951480 | 10731 | lymph node | EBV(+) | Burkitt Lymphoma | Immunocompetent lymphoma |