Dataset: Expression data from post-transplant lymphoproliferative disorder (PTLD) patient samples
In this study we focussed on malignant post-transplant lymphomas. Post-transplant lymphoma is strongly associated with Epstein-Barr Virus...
In this study we focussed on malignant post-transplant lymphomas. Post-transplant lymphoma is strongly associated with Epstein-Barr Virus (EBV) infection in contrast to lymphoma arising in an immunocompetent population. Nevertheless, about 1 in 3 PTLD cases are negative for EBV. We used a microarray to define the gene expression profile of different PTLDs to elucidate the pathogenesis of EBV(+) and EBV(-) PTLD and to define whether EBV(-) PTLD is biologically different from EBV(-) lymphoma arising in an immunocompetent host. PTLD patient samples were randomly selected for RNA extraction and hybridization on an Affymetrix platform. The post-transplant tumors consisted of homogenous sheets of neoplastic cells ensuring reliability of the gene expression data.
- Species:
- human
- Samples:
- 65
- Source:
- E-GEOD-38885
- Updated:
- Dec.12, 2014
- Registered:
- Sep.19, 2014
Factors:
(via ArrayExpress)
| Sample | CHIP NUMBER | EBV STATUS | ORGANISM PART | IMMUNE STATUS | LYMPHOMA SUBTYPE |
|---|---|---|---|---|---|
| GSM951416 | 10706 | EBV(-) | Gut-associated lymphoid tissue | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951417 | 6597 | EBV(-) | Gut-associated lymphoid tissue | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951418 | 10676 | EBV(-) | testis | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951419 | 6554 | EBV(-) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951420 | 6566 | EBV(-) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM95142 | 6569 | EBV(-) | Gut-associated lymphoid tissue | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951422 | 6592 | EBV(-) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951423 | 6606 | EBV(-) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951424 | 6556 | EBV(-) | Gut-associated lymphoid tissue | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951425 | 10730 | EBV(-) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951426 | 10712 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951427 | 10715 | EBV(+) | Waldeyer | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951428 | 6580 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951429 | 10681 | EBV(+) | Gut-associated lymphoid tissue | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951430 | 6568 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM95143 | 10675 | EBV(+) | Waldeyer | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951432 | 10690 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951433 | 10709 | EBV(+) | Waldeyer | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951434 | 6593 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951435 | 10724 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951436 | 6575 | EBV(+) | Urinary tract | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951437 | 10703 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951438 | 6599 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951439 | 10697 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951440 | 6562 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM95144 | 10727 | EBV(+) | Gut-associated lymphoid tissue | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951442 | 10685 | EBV(+) | BALT | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951443 | 10688 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951444 | 6571 | EBV(+) | Urinary tract | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951445 | 6564 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951446 | 10682 | EBV(+) | lymph node | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951447 | 6694 | EBV(+) | Gut-associated lymphoid tissue | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951448 | 6579 | EBV(+) | Gut-associated lymphoid tissue | Post-transplant lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951449 | 6595 | EBV(+) | lymph node | Post-transplant lymphoma | DLBCL (Burkitt-like lymphoma (BLL)) |
| GSM951450 | 6582 | EBV(+) | Waldeyer | Post-transplant lymphoma | DLBCL (Burkitt-like lymphoma (BLL)) |
| GSM95145 | 10696 | EBV(+) | lymph node | Post-transplant lymphoma | DLBCL (Burkitt-like lymphoma (BLL)) |
| GSM951452 | 6602 | EBV(+) | lymph node | Post-transplant lymphoma | DLBCL (Burkitt-like lymphoma (BLL)) |
| GSM951453 | 6585 | EBV(+) | lymph node | Post-transplant lymphoma | DLBCL (Burkitt-like lymphoma (BLL)) |
| GSM951454 | 6590 | EBV(+) | lymph node | Post-transplant lymphoma | DLBCL (Burkitt-like lymphoma (BLL)) |
| GSM951455 | 10733 | EBV(+) | Gut-associated lymphoid tissue | Post-transplant lymphoma | Burkitt Lymphoma |
| GSM951456 | 6598 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951457 | 6561 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951458 | 10710 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951459 | 6607 | EBV(-) | mediastinum | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951460 | 10692 | EBV(-) | Gut-associated lymphoid tissue | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM95146 | 6603 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951462 | 6600 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951463 | 6573 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951464 | 6576 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951465 | 6587 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951466 | 6596 | EBV(-) | Extracranial fronto-parietal | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951467 | 10683 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951468 | 6563 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951469 | 10728 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951470 | 6581 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM95147 | 6570 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951472 | 10719 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951473 | 10714 | EBV(-) | lymph node | Immunocompetent lymphoma | Diffuse large B-cell lymphoma (DLBCL) |
| GSM951474 | 6589 | EBV(-) | lymph node | Immunocompetent lymphoma | DLBCL (Burkitt-like lymphoma (BLL)) |
| GSM951475 | 10725 | EBV(-) | lymph node | Immunocompetent lymphoma | DLBCL (Burkitt-like lymphoma (BLL)) |
| GSM951476 | 10686 | EBV(-) | Gut-associated lymphoid tissue | Immunocompetent lymphoma | DLBCL (Burkitt-like lymphoma (BLL)) |
| GSM951477 | 10713 | EBV(-) | lymph node | Immunocompetent lymphoma | Burkitt Lymphoma |
| GSM951478 | 10677 | EBV(-) | lymph node | Immunocompetent lymphoma | Burkitt Lymphoma |
| GSM951479 | 10695 | EBV(-) | lymph node | Immunocompetent lymphoma | Burkitt Lymphoma |
| GSM951480 | 10731 | EBV(+) | lymph node | Immunocompetent lymphoma | Burkitt Lymphoma |