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Home › Dataset Library › Expression data from post-transplant lymphoproliferative disorder (PTLD) patient samples

Dataset: Expression data from post-transplant lymphoproliferative disorder (PTLD) patient samples

In this study we focussed on malignant post-transplant lymphomas. Post-transplant lymphoma is strongly associated with Epstein-Barr Virus...

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In this study we focussed on malignant post-transplant lymphomas. Post-transplant lymphoma is strongly associated with Epstein-Barr Virus (EBV) infection in contrast to lymphoma arising in an immunocompetent population. Nevertheless, about 1 in 3 PTLD cases are negative for EBV. We used a microarray to define the gene expression profile of different PTLDs to elucidate the pathogenesis of EBV(+) and EBV(-) PTLD and to define whether EBV(-) PTLD is biologically different from EBV(-) lymphoma arising in an immunocompetent host. PTLD patient samples were randomly selected for RNA extraction and hybridization on an Affymetrix platform. The post-transplant tumors consisted of homogenous sheets of neoplastic cells ensuring reliability of the gene expression data.

Species:
human

Samples:
65

Source:
E-GEOD-38885

Updated:
Dec.12, 2014

Registered:
Sep.19, 2014


Factors: (via ArrayExpress)
Sample CHIP NUMBER ORGANISM PART EBV STATUS LYMPHOMA SUBTYPE IMMUNE STATUS
GSM951416 10706 Gut-associated lymphoid tissue EBV(-) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951417 6597 Gut-associated lymphoid tissue EBV(-) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951418 10676 testis EBV(-) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951419 6554 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951420 6566 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM95142 6569 Gut-associated lymphoid tissue EBV(-) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951422 6592 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951423 6606 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951424 6556 Gut-associated lymphoid tissue EBV(-) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951425 10730 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951426 10712 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951427 10715 Waldeyer EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951428 6580 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951429 10681 Gut-associated lymphoid tissue EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951430 6568 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM95143 10675 Waldeyer EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951432 10690 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951433 10709 Waldeyer EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951434 6593 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951435 10724 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951436 6575 Urinary tract EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951437 10703 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951438 6599 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951439 10697 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951440 6562 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM95144 10727 Gut-associated lymphoid tissue EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951442 10685 BALT EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951443 10688 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951444 6571 Urinary tract EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951445 6564 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951446 10682 lymph node EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951447 6694 Gut-associated lymphoid tissue EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951448 6579 Gut-associated lymphoid tissue EBV(+) Diffuse large B-cell lymphoma (DLBCL) Post-transplant lymphoma
GSM951449 6595 lymph node EBV(+) DLBCL (Burkitt-like lymphoma (BLL)) Post-transplant lymphoma
GSM951450 6582 Waldeyer EBV(+) DLBCL (Burkitt-like lymphoma (BLL)) Post-transplant lymphoma
GSM95145 10696 lymph node EBV(+) DLBCL (Burkitt-like lymphoma (BLL)) Post-transplant lymphoma
GSM951452 6602 lymph node EBV(+) DLBCL (Burkitt-like lymphoma (BLL)) Post-transplant lymphoma
GSM951453 6585 lymph node EBV(+) DLBCL (Burkitt-like lymphoma (BLL)) Post-transplant lymphoma
GSM951454 6590 lymph node EBV(+) DLBCL (Burkitt-like lymphoma (BLL)) Post-transplant lymphoma
GSM951455 10733 Gut-associated lymphoid tissue EBV(+) Burkitt Lymphoma Post-transplant lymphoma
GSM951456 6598 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951457 6561 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951458 10710 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951459 6607 mediastinum EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951460 10692 Gut-associated lymphoid tissue EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM95146 6603 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951462 6600 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951463 6573 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951464 6576 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951465 6587 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951466 6596 Extracranial fronto-parietal EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951467 10683 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951468 6563 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951469 10728 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951470 6581 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM95147 6570 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951472 10719 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951473 10714 lymph node EBV(-) Diffuse large B-cell lymphoma (DLBCL) Immunocompetent lymphoma
GSM951474 6589 lymph node EBV(-) DLBCL (Burkitt-like lymphoma (BLL)) Immunocompetent lymphoma
GSM951475 10725 lymph node EBV(-) DLBCL (Burkitt-like lymphoma (BLL)) Immunocompetent lymphoma
GSM951476 10686 Gut-associated lymphoid tissue EBV(-) DLBCL (Burkitt-like lymphoma (BLL)) Immunocompetent lymphoma
GSM951477 10713 lymph node EBV(-) Burkitt Lymphoma Immunocompetent lymphoma
GSM951478 10677 lymph node EBV(-) Burkitt Lymphoma Immunocompetent lymphoma
GSM951479 10695 lymph node EBV(-) Burkitt Lymphoma Immunocompetent lymphoma
GSM951480 10731 lymph node EBV(+) Burkitt Lymphoma Immunocompetent lymphoma

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  • lymphoma

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