Dataset: Expression data from post-transplant lymphoproliferative disorder (PTLD) patient samples
In this study we focussed on malignant post-transplant lymphomas. Post-transplant lymphoma is strongly associated with Epstein-Barr Virus...
In this study we focussed on malignant post-transplant lymphomas. Post-transplant lymphoma is strongly associated with Epstein-Barr Virus (EBV) infection in contrast to lymphoma arising in an immunocompetent population. Nevertheless, about 1 in 3 PTLD cases are negative for EBV. We used a microarray to define the gene expression profile of different PTLDs to elucidate the pathogenesis of EBV(+) and EBV(-) PTLD and to define whether EBV(-) PTLD is biologically different from EBV(-) lymphoma arising in an immunocompetent host. PTLD patient samples were randomly selected for RNA extraction and hybridization on an Affymetrix platform. The post-transplant tumors consisted of homogenous sheets of neoplastic cells ensuring reliability of the gene expression data.
- Species:
- human
- Samples:
- 65
- Source:
- E-GEOD-38885
- Updated:
- Dec.12, 2014
- Registered:
- Sep.19, 2014
Factors:
(via ArrayExpress)
| Sample | IMMUNE STATUS | CHIP NUMBER | EBV STATUS | LYMPHOMA SUBTYPE | ORGANISM PART |
|---|---|---|---|---|---|
| GSM951416 | Post-transplant lymphoma | 10706 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Gut-associated lymphoid tissue |
| GSM951417 | Post-transplant lymphoma | 6597 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Gut-associated lymphoid tissue |
| GSM951418 | Post-transplant lymphoma | 10676 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | testis |
| GSM951419 | Post-transplant lymphoma | 6554 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951420 | Post-transplant lymphoma | 6566 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM95142 | Post-transplant lymphoma | 6569 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Gut-associated lymphoid tissue |
| GSM951422 | Post-transplant lymphoma | 6592 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951423 | Post-transplant lymphoma | 6606 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951424 | Post-transplant lymphoma | 6556 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Gut-associated lymphoid tissue |
| GSM951425 | Post-transplant lymphoma | 10730 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951426 | Post-transplant lymphoma | 10712 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951427 | Post-transplant lymphoma | 10715 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Waldeyer |
| GSM951428 | Post-transplant lymphoma | 6580 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951429 | Post-transplant lymphoma | 10681 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Gut-associated lymphoid tissue |
| GSM951430 | Post-transplant lymphoma | 6568 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM95143 | Post-transplant lymphoma | 10675 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Waldeyer |
| GSM951432 | Post-transplant lymphoma | 10690 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951433 | Post-transplant lymphoma | 10709 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Waldeyer |
| GSM951434 | Post-transplant lymphoma | 6593 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951435 | Post-transplant lymphoma | 10724 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951436 | Post-transplant lymphoma | 6575 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Urinary tract |
| GSM951437 | Post-transplant lymphoma | 10703 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951438 | Post-transplant lymphoma | 6599 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951439 | Post-transplant lymphoma | 10697 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951440 | Post-transplant lymphoma | 6562 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM95144 | Post-transplant lymphoma | 10727 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Gut-associated lymphoid tissue |
| GSM951442 | Post-transplant lymphoma | 10685 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | BALT |
| GSM951443 | Post-transplant lymphoma | 10688 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951444 | Post-transplant lymphoma | 6571 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Urinary tract |
| GSM951445 | Post-transplant lymphoma | 6564 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951446 | Post-transplant lymphoma | 10682 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951447 | Post-transplant lymphoma | 6694 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Gut-associated lymphoid tissue |
| GSM951448 | Post-transplant lymphoma | 6579 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Gut-associated lymphoid tissue |
| GSM951449 | Post-transplant lymphoma | 6595 | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | lymph node |
| GSM951450 | Post-transplant lymphoma | 6582 | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Waldeyer |
| GSM95145 | Post-transplant lymphoma | 10696 | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | lymph node |
| GSM951452 | Post-transplant lymphoma | 6602 | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | lymph node |
| GSM951453 | Post-transplant lymphoma | 6585 | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | lymph node |
| GSM951454 | Post-transplant lymphoma | 6590 | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | lymph node |
| GSM951455 | Post-transplant lymphoma | 10733 | EBV(+) | Burkitt Lymphoma | Gut-associated lymphoid tissue |
| GSM951456 | Immunocompetent lymphoma | 6598 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951457 | Immunocompetent lymphoma | 6561 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951458 | Immunocompetent lymphoma | 10710 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951459 | Immunocompetent lymphoma | 6607 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | mediastinum |
| GSM951460 | Immunocompetent lymphoma | 10692 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Gut-associated lymphoid tissue |
| GSM95146 | Immunocompetent lymphoma | 6603 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951462 | Immunocompetent lymphoma | 6600 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951463 | Immunocompetent lymphoma | 6573 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951464 | Immunocompetent lymphoma | 6576 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951465 | Immunocompetent lymphoma | 6587 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951466 | Immunocompetent lymphoma | 6596 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Extracranial fronto-parietal |
| GSM951467 | Immunocompetent lymphoma | 10683 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951468 | Immunocompetent lymphoma | 6563 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951469 | Immunocompetent lymphoma | 10728 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951470 | Immunocompetent lymphoma | 6581 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM95147 | Immunocompetent lymphoma | 6570 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951472 | Immunocompetent lymphoma | 10719 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951473 | Immunocompetent lymphoma | 10714 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | lymph node |
| GSM951474 | Immunocompetent lymphoma | 6589 | EBV(-) | DLBCL (Burkitt-like lymphoma (BLL)) | lymph node |
| GSM951475 | Immunocompetent lymphoma | 10725 | EBV(-) | DLBCL (Burkitt-like lymphoma (BLL)) | lymph node |
| GSM951476 | Immunocompetent lymphoma | 10686 | EBV(-) | DLBCL (Burkitt-like lymphoma (BLL)) | Gut-associated lymphoid tissue |
| GSM951477 | Immunocompetent lymphoma | 10713 | EBV(-) | Burkitt Lymphoma | lymph node |
| GSM951478 | Immunocompetent lymphoma | 10677 | EBV(-) | Burkitt Lymphoma | lymph node |
| GSM951479 | Immunocompetent lymphoma | 10695 | EBV(-) | Burkitt Lymphoma | lymph node |
| GSM951480 | Immunocompetent lymphoma | 10731 | EBV(+) | Burkitt Lymphoma | lymph node |