Dataset: Expression data from post-transplant lymphoproliferative disorder (PTLD) patient samples
In this study we focussed on malignant post-transplant lymphomas. Post-transplant lymphoma is strongly associated with Epstein-Barr Virus...
In this study we focussed on malignant post-transplant lymphomas. Post-transplant lymphoma is strongly associated with Epstein-Barr Virus (EBV) infection in contrast to lymphoma arising in an immunocompetent population. Nevertheless, about 1 in 3 PTLD cases are negative for EBV. We used a microarray to define the gene expression profile of different PTLDs to elucidate the pathogenesis of EBV(+) and EBV(-) PTLD and to define whether EBV(-) PTLD is biologically different from EBV(-) lymphoma arising in an immunocompetent host. PTLD patient samples were randomly selected for RNA extraction and hybridization on an Affymetrix platform. The post-transplant tumors consisted of homogenous sheets of neoplastic cells ensuring reliability of the gene expression data.
- Species:
- human
- Samples:
- 65
- Source:
- E-GEOD-38885
- Updated:
- Dec.12, 2014
- Registered:
- Sep.19, 2014
Factors:
(via ArrayExpress)
| Sample | ORGANISM PART | CHIP NUMBER | EBV STATUS | LYMPHOMA SUBTYPE | IMMUNE STATUS |
|---|---|---|---|---|---|
| GSM951416 | Gut-associated lymphoid tissue | 10706 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951417 | Gut-associated lymphoid tissue | 6597 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951418 | testis | 10676 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951419 | lymph node | 6554 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951420 | lymph node | 6566 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM95142 | Gut-associated lymphoid tissue | 6569 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951422 | lymph node | 6592 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951423 | lymph node | 6606 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951424 | Gut-associated lymphoid tissue | 6556 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951425 | lymph node | 10730 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951426 | lymph node | 10712 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951427 | Waldeyer | 10715 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951428 | lymph node | 6580 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951429 | Gut-associated lymphoid tissue | 10681 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951430 | lymph node | 6568 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM95143 | Waldeyer | 10675 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951432 | lymph node | 10690 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951433 | Waldeyer | 10709 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951434 | lymph node | 6593 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951435 | lymph node | 10724 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951436 | Urinary tract | 6575 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951437 | lymph node | 10703 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951438 | lymph node | 6599 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951439 | lymph node | 10697 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951440 | lymph node | 6562 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM95144 | Gut-associated lymphoid tissue | 10727 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951442 | BALT | 10685 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951443 | lymph node | 10688 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951444 | Urinary tract | 6571 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951445 | lymph node | 6564 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951446 | lymph node | 10682 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951447 | Gut-associated lymphoid tissue | 6694 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951448 | Gut-associated lymphoid tissue | 6579 | EBV(+) | Diffuse large B-cell lymphoma (DLBCL) | Post-transplant lymphoma |
| GSM951449 | lymph node | 6595 | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Post-transplant lymphoma |
| GSM951450 | Waldeyer | 6582 | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Post-transplant lymphoma |
| GSM95145 | lymph node | 10696 | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Post-transplant lymphoma |
| GSM951452 | lymph node | 6602 | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Post-transplant lymphoma |
| GSM951453 | lymph node | 6585 | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Post-transplant lymphoma |
| GSM951454 | lymph node | 6590 | EBV(+) | DLBCL (Burkitt-like lymphoma (BLL)) | Post-transplant lymphoma |
| GSM951455 | Gut-associated lymphoid tissue | 10733 | EBV(+) | Burkitt Lymphoma | Post-transplant lymphoma |
| GSM951456 | lymph node | 6598 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951457 | lymph node | 6561 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951458 | lymph node | 10710 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951459 | mediastinum | 6607 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951460 | Gut-associated lymphoid tissue | 10692 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM95146 | lymph node | 6603 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951462 | lymph node | 6600 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951463 | lymph node | 6573 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951464 | lymph node | 6576 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951465 | lymph node | 6587 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951466 | Extracranial fronto-parietal | 6596 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951467 | lymph node | 10683 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951468 | lymph node | 6563 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951469 | lymph node | 10728 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951470 | lymph node | 6581 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM95147 | lymph node | 6570 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951472 | lymph node | 10719 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951473 | lymph node | 10714 | EBV(-) | Diffuse large B-cell lymphoma (DLBCL) | Immunocompetent lymphoma |
| GSM951474 | lymph node | 6589 | EBV(-) | DLBCL (Burkitt-like lymphoma (BLL)) | Immunocompetent lymphoma |
| GSM951475 | lymph node | 10725 | EBV(-) | DLBCL (Burkitt-like lymphoma (BLL)) | Immunocompetent lymphoma |
| GSM951476 | Gut-associated lymphoid tissue | 10686 | EBV(-) | DLBCL (Burkitt-like lymphoma (BLL)) | Immunocompetent lymphoma |
| GSM951477 | lymph node | 10713 | EBV(-) | Burkitt Lymphoma | Immunocompetent lymphoma |
| GSM951478 | lymph node | 10677 | EBV(-) | Burkitt Lymphoma | Immunocompetent lymphoma |
| GSM951479 | lymph node | 10695 | EBV(-) | Burkitt Lymphoma | Immunocompetent lymphoma |
| GSM951480 | lymph node | 10731 | EBV(+) | Burkitt Lymphoma | Immunocompetent lymphoma |