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Home › Dataset Library › Intratumoral diversity in Follicular lymphoma

Dataset: Intratumoral diversity in Follicular lymphoma

Follicular lymphoma (FL) shows heterogenous expression of the cell surface B-cell marker, CD20. In order to investigate whether this...

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Follicular lymphoma (FL) shows heterogenous expression of the cell surface B-cell marker, CD20. In order to investigate whether this heterogeneity also marks underlying transcriptional heterogeneity, we sorted tumor B-cells from 8 FL specimens based upon their intermediate or high expression of CD20 and transcriptionally profiled them. CD20 intermediate and CD20 high tumor B-cells were sorted by FACS, RNA extracted, and profiled using Affymetrix U133 plus 2.0 microarrays.

Species:
human

Samples:
18

Source:
E-GEOD-38816

Updated:
Dec.12, 2014

Registered:
Jul.12, 2014


Factors: (via ArrayExpress)
Sample SUBSET AGE TYPE PATIENT IDENTIFIER SEX
GSM95026 Relapse Tumor B-cells 40 Follicular Lymphoma LPJ128 female
GSM950260 CD20int B-cells 40 Follicular Lymphoma LPJ128 female
GSM950259 CD20hi B-cells 40 Follicular Lymphoma LPJ128 female
GSM950258 CD20int B-cells 42 Follicular Lymphoma LPJ114 male
GSM950257 CD20hi B-cells 42 Follicular Lymphoma LPJ114 male
GSM950256 CD20int B-cells 36 Follicular Lymphoma LPJ108 male
GSM950256 CD20int B-cells 36 Follicular Lymphoma LPJ108 male
GSM950254 CD20int B-cells 38 Follicular Lymphoma LPJ103 female
GSM950253 CD20hi B-cells 38 Follicular Lymphoma LPJ103 female
GSM949722 Tumor B-cell 36 Follicular Lymphoma Relapse LPJ041b female
GSM949694 CD20int B-cell 36 Follicular Lymphoma LPJ041a female
GSM949693 CD20hi B-cell 36 Follicular Lymphoma LPJ041a female
GSM949692 CD20int B-cell 29 Follicular Lymphoma LPJ040 male
GSM94969 CD20hi B-cell 29 Follicular Lymphoma LPJ040 male
GSM949690 CD20int B-cell 54 Follicular Lymphoma LPJ023 male
GSM949689 CD20hi B-cell 54 Follicular Lymphoma LPJ023 male
GSM949688 CD20int B-cell 41 Follicular Lymphoma LPJ021 male
GSM949687 CD20hi B-cell 41 Follicular Lymphoma LPJ021 male

Tags

  • cell
  • follicular lymphoma
  • intermediate
  • lymphoma
  • surface

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