Dataset: Transcription profiling by array of kidneys from diabetic wild type and T3-/- mice

Activation of A Disintegrin and A Metalloprotease Domain17 (ADAM17) is involved in nephropathy, but the role of this metalloprotease and its inhibitor TIMP3 in diabetic kidney disease is unclear. We used microarray profiling to find genes differentially expressed in the 2 genotypes which could explain the more severe diabetic kidney disease features observed in T3-/- mice compared to the WT littermates. Total RNA was extracted from 3 WT and 3 Timp3-/- diabetic kidneys

Species:

mouse

Samples:

6

Source:

E-GEOD-36336

Updated:

Dec.12, 2014

Registered:

Nov.12, 2014