Dataset: Expression data from mouse liver treated with metformin
Optimal treatment for nonalcoholic steatohepatitis (NASH) has not yet been established, particularly for individuals without diabetes. We...
Optimal treatment for nonalcoholic steatohepatitis (NASH) has not yet been established, particularly for individuals without diabetes. We examined the effects of metformin, commonly used to treat patients with type 2 diabetes, on liver pathology in a non-diabetic NASH mouse model. Eight-week-old C57BL/6 mice were fed a methionine- and choline-deficient (MCD) + high fat (HF) diet with or without 0.1% metformin for 8 weeks.
- Species:
- mouse
- Samples:
- 12
- Source:
- E-GEOD-35961
- Updated:
- Dec.12, 2014
- Registered:
- Nov.12, 2014
Factors:
(via ArrayExpress)
| Sample | DIET |
|---|---|
| GSM878116 | normal chow (normal) |
| GSM878116 | normal chow (normal) |
| GSM878116 | normal chow (normal) |
| GSM878116 | normal chow (normal) |
| GSM878120 | methionine- and choline-deficient diet+ high fat diet (NASH) |
| GSM878120 | methionine- and choline-deficient diet+ high fat diet (NASH) |
| GSM878120 | methionine- and choline-deficient diet+ high fat diet (NASH) |
| GSM878120 | methionine- and choline-deficient diet+ high fat diet (NASH) |
| GSM878124 | MCD + HF diet mixed with 0.1% metformin (nash metformin) |
| GSM878124 | MCD + HF diet mixed with 0.1% metformin (nash metformin) |
| GSM878124 | MCD + HF diet mixed with 0.1% metformin (nash metformin) |
| GSM878124 | MCD + HF diet mixed with 0.1% metformin (nash metformin) |