Dataset: Transcription profiling of two different mouse models of Huntington's disease - changes caused by Hdh CAG mutation or 3-nitropropionic acid in striatal cells

Affymetrix MG430 2.0 expression levels of wild-type (STHdhQ7/Q7), 3NP-treated wild-type (STHdhQ7/Q7NP), and mutant (STHdhQ111/Q111)...

Registered by ArrayExpress Uploader

View Dataset

Affymetrix MG430 2.0 expression levels of wild-type (STHdhQ7/Q7), 3NP-treated wild-type (STHdhQ7/Q7NP), and mutant (STHdhQ111/Q111) striatal cells Experiment Overall Design: Investigation of HD disease mechanism by gene expression profiling of two HD model systems

Species:: mouse
Samples:: 9
Source:: E-GEOD-3583
PubMed:: 17708681
Updated:: Dec.12, 2014
Registered:: Nov.12, 2014

Factors: (via ArrayExpress)

Sample	COMPOUND	DISEASESTATE	GENOTYPE
GSE3583GSM82441	3-nitropropionic acid	normal	wild_type
GSE3583GSM82441	3-nitropropionic acid	normal	wild_type
GSE3583GSM82441	3-nitropropionic acid	normal	wild_type
GSE3583GSM82444	none	3-NP-induced neurodegeneration model of Huntingtons disease	wild_type
GSE3583GSM82444	none	3-NP-induced neurodegeneration model of Huntingtons disease	wild_type
GSE3583GSM82444	none	3-NP-induced neurodegeneration model of Huntingtons disease	wild_type
GSE3583GSM82447	none	mouse model of Huntingtons disease	huntingtin mutant
GSE3583GSM82447	none	mouse model of Huntingtons disease	huntingtin mutant
GSE3583GSM82447	none	mouse model of Huntingtons disease	huntingtin mutant