Dataset: Transcription profiling of two different mouse models of Huntington's disease - changes caused by Hdh CAG mutation or 3-nitropropionic acid in striatal cells

Affymetrix MG430 2.0 expression levels of wild-type (STHdhQ7/Q7), 3NP-treated wild-type (STHdhQ7/Q7NP), and mutant (STHdhQ111/Q111)...

Registered by ArrayExpress Uploader

View Dataset

Affymetrix MG430 2.0 expression levels of wild-type (STHdhQ7/Q7), 3NP-treated wild-type (STHdhQ7/Q7NP), and mutant (STHdhQ111/Q111) striatal cells Experiment Overall Design: Investigation of HD disease mechanism by gene expression profiling of two HD model systems

Species:: mouse
Samples:: 9
Source:: E-GEOD-3583
PubMed:: 17708681
Updated:: Dec.12, 2014
Registered:: Nov.12, 2014

Factors: (via ArrayExpress)

Sample	COMPOUND	GENOTYPE	DISEASESTATE
GSE3583GSM82441	3-nitropropionic acid	wild_type	normal
GSE3583GSM82441	3-nitropropionic acid	wild_type	normal
GSE3583GSM82441	3-nitropropionic acid	wild_type	normal
GSE3583GSM82444	none	wild_type	3-NP-induced neurodegeneration model of Huntingtons disease
GSE3583GSM82444	none	wild_type	3-NP-induced neurodegeneration model of Huntingtons disease
GSE3583GSM82444	none	wild_type	3-NP-induced neurodegeneration model of Huntingtons disease
GSE3583GSM82447	none	huntingtin mutant	mouse model of Huntingtons disease
GSE3583GSM82447	none	huntingtin mutant	mouse model of Huntingtons disease
GSE3583GSM82447	none	huntingtin mutant	mouse model of Huntingtons disease