Dataset: Transcription profiling of MCF-7 cell lines stably overexpressing constitutively active Raf-1, constitutively active MEK, constitutively active c-erbB-2, or ligand-activatable EGFR as models of overexpressed growth factor signaling
Profiling of MCF-7 cell lines stably overexpressing constitutively active Raf-1, constitutively active MEK, constitutively active...
Profiling of MCF-7 cell lines stably overexpressing constitutively active Raf-1, constitutively active MEK, constitutively active c-erbB-2, or ligand-activatable EGFR as models of overexpressed growth factor signaling, as well as control vector transfected cells (coMCF-7) and control vector transfected cells long-term adapted for estrogen-independent growth (coMCF-7/lt-E2). Experiment Overall Design: Cell lines were profiled in biological triplicates, 18 arrays in all.
- Species:
- human
- Samples:
- 18
- Source:
- E-GEOD-3542
- PubMed:
- 16585219
- Updated:
- Dec.12, 2014
- Registered:
- Jun.19, 2014
Factors:
(via ArrayExpress)
Sample | Genotype |
---|---|
GSE3542GSM81201 | EGFR transfected |
GSE3542GSM81199 | MEK transfected |
GSE3542GSM81192 | long-term E2 independent growth |
GSE3542GSM81205 | Raf-1 transfected |
GSE3542GSM81205 | Raf-1 transfected |
GSE3542GSM81205 | Raf-1 transfected |
GSE3542GSM81191 | sham transfected control |
GSE3542GSM81201 | EGFR transfected |
GSE3542GSM81199 | MEK transfected |
GSE3542GSM81201 | EGFR transfected |
GSE3542GSM81196 | erbB-2 transfected |
GSE3542GSM81199 | MEK transfected |
GSE3542GSM81192 | long-term E2 independent growth |
GSE3542GSM81196 | erbB-2 transfected |
GSE3542GSM81192 | long-term E2 independent growth |
GSE3542GSM81191 | sham transfected control |
GSE3542GSM81196 | erbB-2 transfected |
GSE3542GSM81191 | sham transfected control |