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Home › Dataset Library › Transcription profiling of MCF-7 cell lines stably overexpressing constitutively active Raf-1, constitutively active MEK, constitutively...

Dataset: Transcription profiling of MCF-7 cell lines stably overexpressing constitutively active Raf-1, constitutively active MEK, constitutively active c-erbB-2, or ligand-activatable EGFR as models of overexpressed growth factor signaling

Profiling of MCF-7 cell lines stably overexpressing constitutively active Raf-1, constitutively active MEK, constitutively active...

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Profiling of MCF-7 cell lines stably overexpressing constitutively active Raf-1, constitutively active MEK, constitutively active c-erbB-2, or ligand-activatable EGFR as models of overexpressed growth factor signaling, as well as control vector transfected cells (coMCF-7) and control vector transfected cells long-term adapted for estrogen-independent growth (coMCF-7/lt-E2). Experiment Overall Design: Cell lines were profiled in biological triplicates, 18 arrays in all.

Species:
human

Samples:
18

Source:
E-GEOD-3542

PubMed:
16585219

Updated:
Dec.12, 2014

Registered:
Jun.19, 2014


Factors: (via ArrayExpress)
Sample Genotype
GSE3542GSM81201 EGFR transfected
GSE3542GSM81199 MEK transfected
GSE3542GSM81192 long-term E2 independent growth
GSE3542GSM81205 Raf-1 transfected
GSE3542GSM81205 Raf-1 transfected
GSE3542GSM81205 Raf-1 transfected
GSE3542GSM81191 sham transfected control
GSE3542GSM81201 EGFR transfected
GSE3542GSM81199 MEK transfected
GSE3542GSM81201 EGFR transfected
GSE3542GSM81196 erbB-2 transfected
GSE3542GSM81199 MEK transfected
GSE3542GSM81192 long-term E2 independent growth
GSE3542GSM81196 erbB-2 transfected
GSE3542GSM81192 long-term E2 independent growth
GSE3542GSM81191 sham transfected control
GSE3542GSM81196 erbB-2 transfected
GSE3542GSM81191 sham transfected control

Tags

  • cell
  • estrogen

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