Dataset: In-transit extremity melanoma III
An evaluation of biopsies from patients with in-transit extremity melanoma who have been treated with melphalan in the setting of...
An evaluation of biopsies from patients with in-transit extremity melanoma who have been treated with melphalan in the setting of isolated limb infusion or isolated limb perfusion. Gene expression profiles were obtained from 21 lesions across 19 patients and evaluated for expression that correlated with response to melphalan isolated limb infusion. Chemotherapy response analysis: complete response - CR; partial response - PR; stable disease - SD; progressive disease - PD; not evaluable - n.e.
- Species:
- human
- Samples:
- 21
- Source:
- E-GEOD-34599
- Updated:
- Dec.12, 2014
- Registered:
- Sep.17, 2014
Factors:
(via ArrayExpress)
| Sample | RESPONSE | TREATMENT | GENOTYPE |
|---|---|---|---|
| GSM851708 | stable disease SD | isolated limb infusion w/ melphalan | not specified |
| GSM851709 | complete response CR | isolated limb infusion w/ melphalan | not specified |
| GSM851710 | complete response CR | isolated limb infusion w/ melphalan | Braf-WT Nras-mutant |
| GSM8517 | non-evaluable n.e. | isolated limb infusion w/ melphalan | not specified |
| GSM851712 | non-evaluable n.e. | isolated limb perfusion w/ melphalan | not specified |
| GSM851713 | complete response CR | isolated limb perfusion w/ melphalan | Braf-mutant Nras-WT |
| GSM851714 | progressive disease PD | isolated limb perfusion w/ melphalan | not specified |
| GSM851714 | progressive disease PD | isolated limb perfusion w/ melphalan | not specified |
| GSM851716 | progressive disease PD | isolated limb perfusion w/ melphalan | Braf-mutant Nras-WT |
| GSM851713 | complete response CR | isolated limb perfusion w/ melphalan | Braf-mutant Nras-WT |
| GSM851712 | non-evaluable n.e. | isolated limb perfusion w/ melphalan | not specified |
| GSM851712 | non-evaluable n.e. | isolated limb perfusion w/ melphalan | not specified |
| GSM851712 | non-evaluable n.e. | isolated limb perfusion w/ melphalan | not specified |
| GSM8517 | non-evaluable n.e. | isolated limb infusion w/ melphalan | not specified |
| GSM851709 | complete response CR | isolated limb infusion w/ melphalan | not specified |
| GSM851723 | progressive disease PD | isolated limb infusion w/ melphalan | not specified |
| GSM851724 | partial response PR | isolated limb infusion w/ melphalan | not specified |
| GSM851725 | complete response CR | isolated limb perfusion w/ melphalan | Braf-WT Nras-mutant |
| GSM851723 | progressive disease PD | isolated limb infusion w/ melphalan | not specified |
| GSM851709 | complete response CR | isolated limb infusion w/ melphalan | not specified |
| GSM851708 | stable disease SD | isolated limb infusion w/ melphalan | not specified |