Dataset: Transcriptomic datat of senescence WI-38 cell
Senescence in WI-38 cell context was induce by RASv12 over expression Cellular senescence is a permanent cell cycle arrest that is...
Senescence in WI-38 cell context was induce by RASv12 over expression Cellular senescence is a permanent cell cycle arrest that is triggered by cancer- initiating or promoting events in mammalian cells and is now considered a major tumour suppressor mechanism. Here, we did a transcriptomic analysis and compared WI-38 contol wich is a human fibroblaste cell line and WI-38 that overexpressed RASv12 a G protein that induce senescence. The goal of our project is to compare transciptomic profile of human growing fibroblast (WI-38 control) and senescent human fibroblast (WI-38 OERAS) Comparaison WI-38 vs WI-38 OE RAS
- Species:
- human
- Samples:
- 6
- Source:
- E-GEOD-33710
- Updated:
- Dec.12, 2014
- Registered:
- Jun.18, 2014
Sample | CELL TYPE | GENOTYPE/VARIATION |
---|---|---|
GSM833188 | senescent fibroblast | RASv12 overexpression |
GSM833188 | senescent fibroblast | RASv12 overexpression |
GSM833188 | senescent fibroblast | RASv12 overexpression |
GSM833185 | growing fibroblast | wild type |
GSM833185 | growing fibroblast | wild type |
GSM833185 | growing fibroblast | wild type |