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Home › Dataset Library › Transcriptomic datat of senescence WI-38 cell

Dataset: Transcriptomic datat of senescence WI-38 cell

Senescence in WI-38 cell context was induce by RASv12 over expression Cellular senescence is a permanent cell cycle arrest that is...

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Senescence in WI-38 cell context was induce by RASv12 over expression Cellular senescence is a permanent cell cycle arrest that is triggered by cancer- initiating or promoting events in mammalian cells and is now considered a major tumour suppressor mechanism. Here, we did a transcriptomic analysis and compared WI-38 contol wich is a human fibroblaste cell line and WI-38 that overexpressed RASv12 a G protein that induce senescence. The goal of our project is to compare transciptomic profile of human growing fibroblast (WI-38 control) and senescent human fibroblast (WI-38 OERAS) Comparaison WI-38 vs WI-38 OE RAS

Species:
human

Samples:
6

Source:
E-GEOD-33710

Updated:
Dec.12, 2014

Registered:
Jun.18, 2014


Factors: (via ArrayExpress)
Sample CELL TYPE GENOTYPE/VARIATION
GSM833188 senescent fibroblast RASv12 overexpression
GSM833188 senescent fibroblast RASv12 overexpression
GSM833188 senescent fibroblast RASv12 overexpression
GSM833185 growing fibroblast wild type
GSM833185 growing fibroblast wild type
GSM833185 growing fibroblast wild type

Tags

  • cancer
  • cell
  • fibroblast
  • line
  • protein

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