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Home › Dataset Library › Comparison of the transcriptome of day 3 human embryo with that of the trophectoderm

Dataset: Comparison of the transcriptome of day 3 human embryo with that of the trophectoderm

In humans, the embryonic genome activation (EGA) program is functional by day 3 after fertilization. The 6-8 cell stage embryo (day 3...

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In humans, the embryonic genome activation (EGA) program is functional by day 3 after fertilization. The 6-8 cell stage embryo (day 3 post-fertilization) starts the process of “compaction” that leads to the generation of the tightly organized cell mass of the morula and is followed by differentiation of the morula into a blastocyst. The transition from day 3 embryos to day 5 blastocysts is likely to be controlled by many and specific changes in the expression of different genes. We used mRNA amplification technique and compared the transcriptomes of day 3 human embryos and trophectoderm (TE) cells from day 5 human blastocysts to identify transcripts that are differentially expressed during the embryo-to-TE transition and involved in the TE specification. These six embryo samples were compared to our five human trophectoderm samples that are available in GEO under the following accession numbers: GSM706168 GSM706169 GSM706170 GSM706171 GSM706172

Species:
human

Samples:
6

Source:
E-GEOD-33025

PubMed:
22761758

Updated:
Dec.12, 2014

Registered:
Sep.16, 2014


Factors: (via ArrayExpress)
Sample
GSM818438 1
GSM818439 1
GSM818440 1
GSM818441 1
GSM818448 1
GSM818449 1

Tags

  • blastocyst
  • cell
  • embryo
  • genome

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