Dataset: Time Course of Young Adults Vaccinated with Influenza TIV Vaccine during 2007/08 Flu Season
Systems vaccinology has emerged as an interdisciplinary field that combines systems wide measurements and network and predictive modeling...
Systems vaccinology has emerged as an interdisciplinary field that combines systems wide measurements and network and predictive modeling applied to vaccinology. Here we used the systems vaccinology approach to study the molecular mechanisms underlying the innate responses to the trivalent inactivated influenza (TIV) and live attenuated influenza (LAIV) vaccination in humans, and to identify early gene signatures that predict the magnitude of the antibody responses to influenza vaccination. During the 2007 Influenza season, healthy adults were vaccinated with TIV (9 vaccinees), and blood samples isolated at days 0, 3, 7 post-vaccination. Microarrays were performed using total RNA extracted from the peripheral blood mononuclear cells of vaccinees.
- Species:
- human
- Samples:
- 27
- Source:
- E-GEOD-29614
- Updated:
- Dec.12, 2014
- Registered:
- Sep.16, 2014
| Sample | HAI TITER (DAY 28) - A/ SOLOMON ISLANDS/3/2006 (H1N1) | HAI TITER (DAY 28) - A/WISCONSIN/67/2005 (H3N2) | HAI TITER (DAY 0) - B/MALAYSIA/2506/2004 | HAI TITER (DAY 0) - A/WISCONSIN/67/2005 (H3N2) | HAI TITER (DAY 0) - A/ SOLOMON ISLANDS/3/2006 (H1N1) | HAI TITER (DAY 28) - B/MALAYSIA/2506/2004 | TIME POINT | SUBJECT ID |
|---|---|---|---|---|---|---|---|---|
| GSM733816 | 640 | 160 | 10 | 80 | 40 | 10 | D0 | 12 |
| GSM733817 | 640 | 160 | 10 | 80 | 40 | 10 | D3 | 12 |
| GSM733818 | 640 | 160 | 10 | 80 | 40 | 10 | D7 | 12 |
| GSM733819 | 640 | 160 | 10 | 5 | 40 | 20 | D0 | 16 |
| GSM733820 | 640 | 160 | 10 | 5 | 40 | 20 | D3 | 16 |
| GSM73382 | 640 | 160 | 10 | 5 | 40 | 20 | D7 | 16 |
| GSM733822 | 160 | 80 | 5 | 80 | 160 | 5 | D0 | 18 |
| GSM733823 | 160 | 80 | 5 | 80 | 160 | 5 | D3 | 18 |
| GSM733824 | 160 | 80 | 5 | 80 | 160 | 5 | D7 | 18 |
| GSM733825 | 640 | 80 | 5 | 5 | 160 | 5 | D0 | 21 |
| GSM733826 | 640 | 80 | 5 | 5 | 160 | 5 | D3 | 21 |
| GSM733827 | 640 | 80 | 5 | 5 | 160 | 5 | D7 | 21 |
| GSM733828 | 2560 | 20 | 5 | 5 | 5 | 5 | D0 | 23 |
| GSM733829 | 2560 | 20 | 5 | 5 | 5 | 5 | D3 | 23 |
| GSM733830 | 2560 | 20 | 5 | 5 | 5 | 5 | D7 | 23 |
| GSM73383 | 80 | 160 | 5 | 5 | 40 | 40 | D0 | 29 |
| GSM733832 | 80 | 160 | 5 | 5 | 40 | 40 | D3 | 29 |
| GSM733833 | 80 | 160 | 5 | 5 | 40 | 40 | D7 | 29 |
| GSM733834 | 2560 | 160 | 5 | 20 | 40 | 80 | D0 | 32 |
| GSM733835 | 2560 | 160 | 5 | 20 | 40 | 80 | D3 | 32 |
| GSM733836 | 2560 | 160 | 5 | 20 | 40 | 80 | D7 | 32 |
| GSM733837 | 40 | 640 | 5 | 40 | 5 | 5 | D0 | 35 |
| GSM733838 | 40 | 640 | 5 | 40 | 5 | 5 | D3 | 35 |
| GSM733839 | 40 | 640 | 5 | 40 | 5 | 5 | D7 | 35 |
| GSM733840 | 160 | 2560 | 80 | 2560 | 80 | 80 | D0 | 39 |
| GSM73384 | 160 | 2560 | 80 | 2560 | 80 | 80 | D3 | 39 |
| GSM733842 | 160 | 2560 | 80 | 2560 | 80 | 80 | D7 | 39 |