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Home › Dataset Library › Exon-Level Expression Data from Primary Human B Cells and Lymphoblastoid Cell Lines (LCLs) on HuEx and U133 2.0 plus Platforms

Dataset: Exon-Level Expression Data from Primary Human B Cells and Lymphoblastoid Cell Lines (LCLs) on HuEx and U133 2.0 plus Platforms

Eptstein-Barr Virus, an oncogenic herpesvirus, infects and immortalizes human B cells in culture into indefinitely-prolerifating LCLs....

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Eptstein-Barr Virus, an oncogenic herpesvirus, infects and immortalizes human B cells in culture into indefinitely-prolerifating LCLs. We examined the gene expression of primary B cells during the process of infection and growth transformation at the exon level to analyze virus-induced changes in expression and exon usage. 4 samples each of total RNA were extracted from purified resting B Cells and monoclonal LCLs, for a total of 8. These samples were subjected to either Human Exon Array 1.0 or Affymetrix U133 2.0 plus. Data was then RMA normalized and analyzed using SplicerEx

Species:
human

Samples:
8

Source:
E-GEOD-29301

Updated:
Dec.12, 2014

Registered:
Sep.16, 2014


Factors: (via ArrayExpress)
Sample CELL TYPE INFECTION
GSM724240 Purified B Cells, from negative selection of PBMCs uninfected
GSM724240 Purified B Cells, from negative selection of PBMCs uninfected
GSM724240 Purified B Cells, from negative selection of PBMCs uninfected
GSM724240 Purified B Cells, from negative selection of PBMCs uninfected
GSM724244 Lymphoblastoid Cell Line, EBV-infected, monoclonal Epstein-Barr virus infected, immortalized
GSM724244 Lymphoblastoid Cell Line, EBV-infected, monoclonal Epstein-Barr virus infected, immortalized
GSM724244 Lymphoblastoid Cell Line, EBV-infected, monoclonal Epstein-Barr virus infected, immortalized
GSM724244 Lymphoblastoid Cell Line, EBV-infected, monoclonal Epstein-Barr virus infected, immortalized

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  • exon

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