Dataset: Exon-Level Expression Data from Primary Human B Cells and Lymphoblastoid Cell Lines (LCLs) on HuEx and U133 2.0 plus Platforms
Eptstein-Barr Virus, an oncogenic herpesvirus, infects and immortalizes human B cells in culture into indefinitely-prolerifating LCLs....
Eptstein-Barr Virus, an oncogenic herpesvirus, infects and immortalizes human B cells in culture into indefinitely-prolerifating LCLs. We examined the gene expression of primary B cells during the process of infection and growth transformation at the exon level to analyze virus-induced changes in expression and exon usage. 4 samples each of total RNA were extracted from purified resting B Cells and monoclonal LCLs, for a total of 8. These samples were subjected to either Human Exon Array 1.0 or Affymetrix U133 2.0 plus. Data was then RMA normalized and analyzed using SplicerEx
- Species:
- human
- Samples:
- 8
- Source:
- E-GEOD-29301
- Updated:
- Dec.12, 2014
- Registered:
- Sep.16, 2014
Factors:
(via ArrayExpress)
Sample | CELL TYPE | INFECTION |
---|---|---|
GSM724240 | Purified B Cells, from negative selection of PBMCs | uninfected |
GSM724240 | Purified B Cells, from negative selection of PBMCs | uninfected |
GSM724240 | Purified B Cells, from negative selection of PBMCs | uninfected |
GSM724240 | Purified B Cells, from negative selection of PBMCs | uninfected |
GSM724244 | Lymphoblastoid Cell Line, EBV-infected, monoclonal | Epstein-Barr virus infected, immortalized |
GSM724244 | Lymphoblastoid Cell Line, EBV-infected, monoclonal | Epstein-Barr virus infected, immortalized |
GSM724244 | Lymphoblastoid Cell Line, EBV-infected, monoclonal | Epstein-Barr virus infected, immortalized |
GSM724244 | Lymphoblastoid Cell Line, EBV-infected, monoclonal | Epstein-Barr virus infected, immortalized |