Dataset: Ath29 congenic mice - gene expression in aorta
A congenic mouse line was constructed by introgressing a C3H chromosome 9 region harboring Ath29 into the C57BL/6 apoE-deficient...
A congenic mouse line was constructed by introgressing a C3H chromosome 9 region harboring Ath29 into the C57BL/6 apoE-deficient background. RNA was extracted from aorta using a QIAGEN kit . Total RNA was pooled in an equal amount from 3 mice for each group. Standard Affymetrix procedures were performed using 8ug of total RNA. Microarrays were used to detect gene expression in the aorta of Ath29 congenic mice and C57BL/6 apoE-deficient mouse strains fed a chow or western diet. 4 groups of mice were studied: C57BL/6 apoE-/- control mice and Ath29 congenic mice fed a chow or Western diet. After fed a Western diet for 2 weeks, aorta was harvested and total RNA prepared.
- Species:
- mouse
- Samples:
- 4
- Source:
- E-GEOD-29149
- Updated:
- Dec.12, 2014
- Registered:
- Nov.11, 2014
Sample | DISEASE STATE | GENOTYPE | DIET |
---|---|---|---|
GSM721548 | Resistance to atherosclerosis | Ath29 congenic mice | chow |
GSM721549 | Atherosclerosis | C57BL/6 apoE-/- mice | chow |
GSM721550 | Resistance to atherosclerosis | Ath29 congenic mice | western |
GSM72155 | Atherosclerosis | C57BL/6 apoE-/- mice | western |