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Home › Dataset Library › Expression data of human pulmonary arterial smooth muscle cells (PASMCs) treated with BMP-4

Dataset: Expression data of human pulmonary arterial smooth muscle cells (PASMCs) treated with BMP-4

Smad1/5 are transcription factors that engage in BMP-induced transcription. We determined and analyzed Smad1/5 binding sites by ChIP-...

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Smad1/5 are transcription factors that engage in BMP-induced transcription. We determined and analyzed Smad1/5 binding sites by ChIP-sequencing. We used expression microarrays to compare the Smad1/5 binding sites identified by ChIP-seq to BMP-induced gene expressions. PASMCs were treated with 50 ng/ml BMP-4 for 0, 2, or 24 hrs. RNA was extracted and hybridized on Affymetrix microarrays.

Species:
human

Samples:
3

Source:
E-GEOD-28847

PubMed:
21764776

Updated:
Dec.12, 2014

Registered:
Sep.16, 2014


Factors: (via ArrayExpress)
Sample TREATMENT TREATMENT DURATION
GSM714355 none 0 hrs
GSM714356 BMP-4 2 hrs
GSM714357 BMP-4 24 hrs

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