Dataset: Expression data of human pulmonary arterial smooth muscle cells (PASMCs) treated with BMP-4
Smad1/5 are transcription factors that engage in BMP-induced transcription. We determined and analyzed Smad1/5 binding sites by ChIP-...
Smad1/5 are transcription factors that engage in BMP-induced transcription. We determined and analyzed Smad1/5 binding sites by ChIP-sequencing. We used expression microarrays to compare the Smad1/5 binding sites identified by ChIP-seq to BMP-induced gene expressions. PASMCs were treated with 50 ng/ml BMP-4 for 0, 2, or 24 hrs. RNA was extracted and hybridized on Affymetrix microarrays.
- Species:
- human
- Samples:
- 3
- Source:
- E-GEOD-28847
- PubMed:
- 21764776
- Updated:
- Dec.12, 2014
- Registered:
- Sep.16, 2014
Factors:
(via ArrayExpress)
Sample | TREATMENT | TREATMENT DURATION |
---|---|---|
GSM714355 | none | 0 hrs |
GSM714356 | BMP-4 | 2 hrs |
GSM714357 | BMP-4 | 24 hrs |