Dataset: The effect of sirtuin 6 overexpression on TNFa stimulation.
SIRT6 has been implicated in a range of biological processes including inflammation, aging and the control of metabolism. Hence...
SIRT6 has been implicated in a range of biological processes including inflammation, aging and the control of metabolism. Hence inhibitors or activators of SIRT6 have the potential to be therapeutics for a number of indications. Genome wide expression studies were used to investigate the effect of overexpression of SIRT6 and mutant SIRT6 on a wide range of NFκB dependent gene expression HEK293 cells were transfected with expression vectors encoding wild type SIRT6 or the H133W mutant followed by stimulation with TNFα for one hour.
- Species:
- human
- Samples:
- 24
- Source:
- E-GEOD-28548
- Updated:
- Dec.12, 2014
- Registered:
- Sep.16, 2014
Factors:
(via ArrayExpress)
| Sample |
|---|
| GSM707024 1 |
| GSM707025 1 |
| GSM707026 1 |
| GSM707027 1 |
| GSM707028 1 |
| GSM707029 1 |
| GSM707030 1 |
| GSM707031 1 |
| GSM707032 1 |
| GSM707033 1 |
| GSM707034 1 |
| GSM707035 1 |
| GSM707036 1 |
| GSM707037 1 |
| GSM707038 1 |
| GSM707039 1 |
| GSM707040 1 |
| GSM707041 1 |
| GSM707042 1 |
| GSM707043 1 |
| GSM707044 1 |
| GSM707045 1 |
| GSM707046 1 |
| GSM707047 1 |