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Home › Dataset Library › Human airway epithelial responses to rhinovirus infection and cigarette smoke extract alone and in combination

Dataset: Human airway epithelial responses to rhinovirus infection and cigarette smoke extract alone and in combination

This study was performed to test the hypothesis that cigarette smoke extract would alter the responses of primary cultures of human...

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This study was performed to test the hypothesis that cigarette smoke extract would alter the responses of primary cultures of human bronchial epithelial cells to infection with purified human rhinovirus 16. The data show marked alterations in rhinovirus-induced expression profiles of a number of genes in the presence of cigarette smoke extract (CSE). Cultured epithelial cells from each of 4 donors were exposed to medium alone, rhinovirus 16 (RV16) alone, CSE alone, or RV16 in the presence of CSE. After a 24 h incubation gene expression was assessed.

Species:
human

Samples:
16

Source:
E-GEOD-27973

Updated:
Dec.12, 2014

Registered:
Sep.15, 2014


Factors: (via ArrayExpress)
Sample DONOR STRESS
GSM692115 1 medium
GSM692116 1 RV16
GSM692117 1 CSE
GSM692118 1 RV16+CSE
GSM692119 2 medium
GSM692120 2 RV16
GSM69212 2 CSE
GSM692122 2 RV16+CSE
GSM692123 3 medium
GSM692124 3 RV16
GSM692125 3 CSE
GSM692126 3 RV16+CSE
GSM692127 4 medium
GSM692128 4 RV16
GSM692129 4 CSE
GSM692130 4 RV16+CSE

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